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The acoustical properties of deoxygenated sickle cell blood and hemoglobin S solution

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Abstract

Experimental data are presented to show that the acoustical properties in low oxygen tension sickle cell blood and deoxyhemoglobin S solution are altered, probably due to the crystallization of hemoglobin S. The velocity of propagation is only slightly higher than that of normal blood at the same hemoglobin concentration. The attenuation coefficient shows noted increase and the scattering cross section is found to be about four times larger at 5 MHz. The increase in attenuation has been determined to arise mainly from increased absorption.

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Authors and Affiliations

  1. Providence Medical Center and Institute of Applied Physiology and Medicine, Seattle, 98122, Washington

    K. K. Shung & J. M. Reid

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  1. K. K. Shung
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  2. J. M. Reid
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This work has been supported by NIH Grant HL14785.

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Shung, K.K., Reid, J.M. The acoustical properties of deoxygenated sickle cell blood and hemoglobin S solution. Ann Biomed Eng 5, 150–156 (1977). https://doi.org/10.1007/BF02364015

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  • DOI: https://doi.org/10.1007/BF02364015

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