Annals of Biomedical Engineering

, Volume 7, Issue 2, pp 117–125 | Cite as

The response of the myelinated nerve fiber to short duration biphasic stimulating currents

  • Christopher van den Honert
  • J. Thomas Mortimer
Article

Abstract

The response of a single Node of Ranvier to short duration biphasic stimulating currents was studied. Such stimulus patterns are known to be less likely to induce tissue damage than are longer monophasic stimuli. The presence of the anodic phase of a pulse pair was found to abolish excitation in cases where the cathodic phase alone was near threshold. In addition, peak twitch force from the tibialis anterior muscle of cat was found to be reduced by the use of biphasic motor nerve stimulation in place of monophasic stimulation. The abolition phenomenon could be eliminated by the introduction of a delay of 100 μs between the phases of a biphasic stimulus waveform.

Keywords

Short Duration Nerve Fiber Tissue Damage Nerve Stimulation Single Node 

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Copyright information

© Pergamon Press Ltd. 1979

Authors and Affiliations

  • Christopher van den Honert
    • 1
    • 2
  • J. Thomas Mortimer
    • 1
    • 2
  1. 1.Applied Neural Control Laboratory Department of Biomedical EngineeringCase Western Reserve UniversityCleveland
  2. 2.Engineering Design CenterCase Western Reserve UniversityCleveland

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