Skip to main content

Advertisement

Log in

An autopsy case of pseudosarcoma of the common bile duct

  • Published:
Journal of Gastroenterology Aims and scope Submit manuscript

Abstract

An autopsy case of pseudosarcoma in the common bile duct is reported. An 82-year-old Japanese male complaining of jaundice was admitted to our hospital; he was examined by abdominal ultrasonography (US), revealing biliary calculus, dilatation of the common bile duct, and choledocholithiasis, considered to be the possible cause of the obstructive jaundice.

Endoscopic retrograde biliary drainage (ERBD) and cholangioscopy were performed concurrently, revealing a vaguely whitish tumor near the papilla of Vater. Two months later, the patient died from complications of the liver, infection, and disseminated intravascular coagulation (DIC). An autopsy study revealed tumor cells with extreme pleomorphic changes, growing diffusely, very like sarcoma. Further examination revealed epithelioid arrangements in the metastatic lymph node. Twelve kinds of immunohistochemical examination showed a positive reaction, reflecting the presence of an epithelioid cytoskeleton. Of 28 cases of true and pseudosarcoma of the biliary system reported in the Japanese literature, only 1 case was reported, in 1990, to involve the common bile duct. We therefore report the present case of pseudosarcoma of the common bile duct.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Appleman HD, Coopersmith N. Pleomorphic spindle-cell carcinoma of the gallbladder: Relation to sarcoma of the gallbladdel. Cancer 1970;25:534–541.

    Google Scholar 

  2. Piehler JM, Crichlow RW. Primary carcinoma of the gallbladder. Surg Gynecol Obstet 1978;147:929–942.

    CAS  PubMed  Google Scholar 

  3. Alpers CE, Smucker EA. Pleomorphic carcinoma of the gallbladder. Case report and ultrastructural study. Ultrastruct Pathol 1984;6:29–38.

    CAS  PubMed  Google Scholar 

  4. Albores-Saavedra J, Cruz-Ortiz H, Acantara-Vazques A, et al. Unusual types of gallbladder carcinoma. A report of 16 cases. Arch Pathol Lab Med 1981;105:287–293.

    CAS  PubMed  Google Scholar 

  5. Lane N. Pseudosarcoma associated with squamous cell carcinoma of the mouth, face, and larynx. Report of ten cases. Cancer 1957;10:19–41.

    CAS  PubMed  Google Scholar 

  6. Inoshita S, Iwashita A., Enjoji M. Carcinosarcoma of the gallbladder. Report of a case and review of the literature. Acta Pathol Jpn 1986;36:913–920.

    CAS  PubMed  Google Scholar 

  7. Martin MR, Kahn LB. So-called pseudosarcoma of the esophagus. Nodal metastases of the spindle cell element. Arch Pathol Lab Med 1977;101:604–609.

    CAS  PubMed  Google Scholar 

  8. Battifora H. Spindle cell carcinoma: Ultrastructural evidence of squamous origin and collagen production by the tumor cells. Cancer 1976;37:2275–2282.

    CAS  PubMed  Google Scholar 

  9. Lichtiger B, Mackay B, Tessmer CT. Spindle cell variant of squamous carcinoma. Cancer 1970;26:1311–1320.

    CAS  PubMed  Google Scholar 

  10. Ooi A, Kawahara E, Okada Y, et al. Carcimosarcoma of the esophagus. An immunohistochemical electron microscopic study. Acta Pathol Jpn 1986;36:151–159.

    CAS  PubMed  Google Scholar 

  11. Born M, Ramey G, Ryan SF, Gordon PE. Carcinosarcoma of the gallbladder. Cancer 1984;53:2171–2177.

    CAS  PubMed  Google Scholar 

  12. Sumikawa M, Ogawa H, Kaibara N, Adachi H. A case of pseudocarcinosarcoma of the bile duct (in Japanese). Surgery 1990;52:177–179.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kagami, A., Nikaidou, T., Miyairi, M. et al. An autopsy case of pseudosarcoma of the common bile duct. J Gastroenterol 29, 525–530 (1994). https://doi.org/10.1007/BF02361255

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02361255

Key words

Navigation