Hippocampal morphology in the inbred mouse strains NZB and CBA/H and their reciprocal congenics for the nonpseudoautosomal region of the Y chromosome
The effects of the nonpseudoautosomal region of the Y chromosome (Y NPAR ) on hippocampal morphology have been investigated in the inbred mouse strains NZB/B1NJ and CBA/H, using comparisons between the two parentals and their respective congenics N.H-Y NPAR and H.N-Y NPAR . Results obtained depend upon the hippocampal variable measured. Y NPAR had no effect on the sizes of the stratum oriens, hilus, or mossy fiber terminal fields (both suprapyramidal and intra- and infrapyramidal). However, in interaction with the strain background, it affected the strata lacunosum-moleculare, radiatum, and pyramidale. Possible relationships among gene(s), mossy fiber terminal fields, and intermale aggression are discussed.
Key WordsIntermale aggression congenic strains hippocampus mossy fibers NZB/B1NJ CBA/H Y chromosome
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