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Blockage of LSD binding at its high affinity site on synaptosomal membranes by 1-methyl-1,2,5,6-tetrahydropyridine-N,N-diethyl-carboxamide

  • Specialia Biologica
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Résumé

Par dialyse d'équilibre on a montré que le 1-methyl-1,2,5,6-tetrahydropyridine-N,N-diethylcarboxamide (THPC) empêche le LSD de se lier aux membranes des synaptosomes. Ce résultat correspond à un effet du THPC qui est de réduire la nocivité de LSD.

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Authors and Affiliations

  1. The Neurosciences Program, University of Alabama Medical Center, University Station, 35294, Birmingham, Alabama, USA

    S. T. Christian, L. D. McClain, R. D. Morin & F. Benington

  2. Department of Psychiatry, University of Alabama Medical Center, University Station, 35294, Birmingham, Alabama, USA

    S. T. Christian, L. D. McClain, R. D. Morin & F. Benington

Authors
  1. S. T. Christian
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  2. L. D. McClain
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  3. R. D. Morin
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  4. F. Benington
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Christian, S.T., McClain, L.D., Morin, R.D. et al. Blockage of LSD binding at its high affinity site on synaptosomal membranes by 1-methyl-1,2,5,6-tetrahydropyridine-N,N-diethyl-carboxamide. Experientia 31, 910–911 (1975). https://doi.org/10.1007/BF02358845

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  • DOI: https://doi.org/10.1007/BF02358845

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