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Influence of methylxanthines on aniline disappearance and metabolism in rats

  • Specialia Chimica, Biochimica
  • Published:
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Zusammenfassung

Eine Induktion der Mikrosomalenzyme der Leber, gemessen in vitro, wurde beobachtet, wenn hohe Dosen von Methylxanthinen an Ratten verabreicht wurde. Wenn den Versuchstieren gleich hohe Dosen von den obengenannten Substanzen verabreicht wurden, die Aktivität der arzneimittelabbauenden Enzyme jedoch in vivo gemessen wurde, so war kein Unterschied zur Kontrollgruppe festzustellen.

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Authors and Affiliations

  1. Biological Laboratories, Nestlé Products Technical Assistance Company Limited, CH-1350, Orbe, (Switzerland)

    H. U. Aeschbacher

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  1. H. U. Aeschbacher
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Additional information

Acknowledgments. The author is indebted to Ms.R. Acheson, Dr.L. Vuataz and Dr.R. Stalder for their advice.

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Aeschbacher, H.U. Influence of methylxanthines on aniline disappearance and metabolism in rats. Experientia 31, 894–896 (1975). https://doi.org/10.1007/BF02358836

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  • DOI: https://doi.org/10.1007/BF02358836

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