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In vitro metabolism of ethionine, N-acetyl-ethionine and N-acetylmethionine by rat liver microsomes

  • Specialia Chimica, Biochimica
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Summary

Rat liver microsomes deacetylated N-acetylethionine and N-acetyl-methionine to ethionine and methionine. The deacetylation of N-acetylmethionine was more rapid than the deacetylation of N-acetylethionine. Ethionine was slowly converted to ethionine sulfoxide by the microsomal preparations. N-Acetylethionine and N-acetylmethionine were not oxidized by the microsomes.

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Authors and Affiliations

  1. Department of Animal and Dairy Sciences, Auburn University, School of Agriculture, 36830, Auburn, Alabama, USA

    K. T. Francis & R. C. Smith

Authors
  1. K. T. Francis
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  2. R. C. Smith
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Additional information

This work was supported by Public Health Service Research Grant No. HE-02615 from the National Heart Institute and by Hatch and State funds of Auburn University Agricultural Experiment Station.

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Francis, K.T., Smith, R.C. In vitro metabolism of ethionine, N-acetyl-ethionine and N-acetylmethionine by rat liver microsomes. Experientia 31, 890–891 (1975). https://doi.org/10.1007/BF02358833

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  • DOI: https://doi.org/10.1007/BF02358833

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