Abstract
The utility of magnetic resonance imaging (MRI) in the diagnosis of acute cholecystitis was evaluated in 72 consecutive individuals (5 healthy, 13 with chronic cholecystitis andsilent gallbladder stones, 43 without biliary or diffuse liver disease, and 11 with acute cholecystitis and gallbladder stones) with a 0.5-T superconducting unit. On the T1-weighted (500/20) and less T1-weighted axial spin-echo images (620/25), the liver/gallbladder signal intensity ratio (mean±SD) was 2.5±0.51 (n=5) and 1.8±0.29 (n=8) in acute cholecystitis; 0.9±0.42 (n=6) and 1.0±0.29 (n=9) in chronic cholecystitis; and 0.9±0.14 (n=5) and 0.8±0.19 (n=43) in normal gallbladder, respectively. Our results indicate that the liver/gallbladder signal intensity ratio on the T1-weighted image may be a simple and reliable indicator for the diagnosis of acute cholecystitis; we suggest further investigation to confirm these results.
Similar content being viewed by others
References
Hricak H, Filly RA, Margulis AR, et al. Work in progress: Nuclear magnetic resonance imaging of the gallbladder. Radiology 1983;147:481–484.
Demas BE, Hricak H, Moseley M, et al. Gallbladder bile: An experimental study in dogs using MR imaging and proton MR spectroscopy. Radiology 1985;157:453–455.
Kang YS, Pope CF, Gore JC. Alterations in MR relaxation of normal canine gallbladder bile during fasting. Mag Res Imag 1986;4:399–406.
Bakan DA, Barnhart JL. Determination of parameters effecting proton relaxation of hepatic and gallbladder biles in dogs. Hepatology 1988;8:341–346.
Weissleder R, Stark DD, Compton CC, et al. Cholecystitis: Diagnosis by MR imaging. Mag Res Imag 1988;6:345–348.
McCarthy S, Hricak H, Cohen M, et al. Cholecystitis: Detection with MR imaging. Radiology 1986;158:333–336.
Loflin TG, Simeone JF, Mueller PR, et al. Gallbladder bile in cholecystitis: In vitro MR evaluation. Radiology 1985;157:457–459.
Weedon D. Pathology of the gallbladder. New York: Masson, 1984;90–146.
Chinn DH, Miller EI, Piper N. Hemorrhagic Cholecystitis, sonographic appearance and clinical presentation. J Ultrasound Med 1987;6:313–317.
McNeil BJ, Keeler E, Adelstein SJ. Primer on certain elements of medical decision making. N Engl J Med 1975;293:211–215.
Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982;143:29–36.
Bottomley PA, Foster TH, Argersinger RE, Pfeifer LM. A review of normal tissue hydrogen NMR relaxation times and relaxation mechanisms from 1–100 MHz: Dependence on tissue type, NMR frequency, temperature, species, excision, and age. Med Phys 1984;11(4):425–448.
Svanvik J, Thornell E, Zettergren L. Gallbladder function in experimental cholecystitis. Surgery 1981;89:500–506.
Jivegard L, Thornell E, Svanvik J. Pathophysiology of acute obstructive cholecystitis: Implications for non-operative management. Br J Surg 1987;74:1084–1086.
Igimi H, Yamamoto F, Lee SP. Gallbladder mucosal function: Studies in absorption and secretion in humans and cultured dog gallbladder epithelium. Am J Physiol 1992;263 (Gastrointest Liver Physiol 26): G69–74.
Lee JKT, Sagel SS, Stanley RJ. Computed body tomography with MRI correlation. 2nd ed. New York: Raven, 1989;61–70.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Pu, Y., Yamamoto, F., Igimi, H. et al. A comparative study usefulness of magnetic resonance imaging in the diagnosis of acute cholecystitis. J Gastroenterol 29, 192–198 (1994). https://doi.org/10.1007/BF02358682
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02358682