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Tropical Animal Health and Production

, Volume 2, Issue 4, pp 223–234 | Cite as

Comparative anthelmintic tests in sheep and goats infected with gastro-intestinal nematodes and lungworms in Iran

  • A. A. Shahlapour
  • A. H. Eslami
  • H. Eliazian
Article

Summary

In three controlled experiments the efficiency of thiabendazole, tetramisole, diethylcarbamazine citrate, emetine hydrochloride and iodine was tested against gastro-intestinal nematodes and lungworms in naturally infected sheep and goats in Iran.

An oral dose of either 10 or 15 mg/kg bodyweight of tetramisole, and 100 mg/kg (twice the normally recommended dose) of thiabendazole gave excellent results against all stages of nematodes of the alimentary tract, andDictyocaulus filaria and Protostrongylus spp. in the lungs. Thiabendazole was also shown to have some effect againstMuellerius spp.

Diethylcarbamazine citrate, given in three daily doses of 20 mg/kg, gave good results againstDictyocaulus filaria andProtostrongylus spp., respectively.

Emetine was toxic at 3 mg/kg but appeared safe and effective againstP. rufescens at one mg/kg. Efficiency againstMuellerius at this dose was 68 per cent.

Iodine gave no noticeable effect againstMuellerius spp. andProtostrongylus spp.

The use of these anthelmintics for the control of mixed infections of gastrointestinal nematodes and lungworms in sheep and goats is discussed.

Keywords

Iodine Mixed Infection Noticeable Effect Alimentary Tract Thiabendazole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Résumé

Dans trois essais contrôlés, l'efficacité du thiabendazole, du tétramisole, du citrate de diéthylcarbamazine, du chlorhydrate d'émétine et de l'iodine fut éprouvée sur des nématodes gastro-intestinaux et pulmonaires chez des chèvres et des moutons naturellement infestés en Iran.

Une dose orale de 10 ou 15 mg/kg vif de tétramisole et de 100 mg/kg (deux fois la dose recommandée) de thiabendazole donna d'excellents résultats sur tous les stades des nématodes du tractus digestif et surDictyocaulus filaria etProtostrongylus spp. dans les poumons. Le thibendazole aussi se révèle efficace dans une certaine mesure contreMuellerius spp.

Le citrate de diéthylcarbamazine, donné trois jours de suite à 20 mg/kg donna de bons résultats contreD. filaria etProtostrongylus spp.

L'émétine était toxique à 3 mg/kg, mais apparut inoffensive et efficace contreP. rufescens à la dose de 1 mg/kg. A cette dose, son efficacité contreMuellerius était de 68 p. 100.

L'iodine ne fournit aucun résultat appréciable contreMuellerius spp. etProtostrongylus spp.

L'emploi de ces anthelminthiques pour la prophylaxie de ces infestations mixtes des moutons et des chèvres est discuté.

Sumario

En tres experimentos controlados se probóla eficiencia del thiabendazole, tetramizole, citrato de dietil carbamazine, clorhidrato de emetina y iodo contra nemátodes gastro-intestinales y parásitos pulmonares en ovinos y caprinos de Irán, naturalmente infectados.

Una dosis oral de 10 ó 15 mg/kg de peso corporal, de tetramizole y 100 mg/kg (El doble de la dosis normalmente recomendada) de thiabendazole dió resultados excelentes contra todos los estadíos de nemátodes del tracto digestivo, yDictyocaulus filaria yProtostrongylus spp. de los pulmones. El thiabendazole también tuvo un pequeño efecto contraMuellerius spp. El citrato de dietil carbamazine administrado en tres dosis diarias de 20 mg/kg, dió buenos resultados contraDictyocaulus filaria yProtostrongylus spp., respectivamente. La emetina fué tóxica dada en 3 mg/kg, pero pareció segura y efectiva contraP. rufescens cuando fué administrada a razón de 1 mg/kg. La eficiencia contra elMeullerius en esta concentración fué del 68 per cent.

Ei iodo no dió ningun efecto notable, contraMuellerius spp. yProtostrongylus spp. Se discute el uso de estos anti-helmînticos para el control de infecciones mixtas de nemátodes gastro-intestinales y pulmonares.

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Copyright information

© E. & S. Livingstone 1970

Authors and Affiliations

  • A. A. Shahlapour
    • 1
  • A. H. Eslami
    • 2
  • H. Eliazian
    • 1
  1. 1.Razi InstituteMeshedIran
  2. 2.Veterinary FacultyUniversity of TeheranIran

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