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Ulcerative colitis complicated by gastroduodenal lesions

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Abstract

A case of ulcerative colitis complicated with gastric and duodenal lesions is reported. The patient was a 17-year-old male who was admitted with bloody diarrhea and abdominal pain. Based on the endoscopic and histological findings of the colon, a diagnosis of ulcerative colitis was made. Upper gastrointestinal endoscopy showed multiple erosions and granular changes in the antral greater curvature of the stomach and descending portion of the duodenum. Histological examination of the stomach and duodenum revealed marked inflammatory cell infiltration and crypt abscesses. Clinically, the gastric and duodenal lesions did not respond to antiulcer drugs, but were alleviated by steroid. It was concluded that the pathogenesis of the gastric and duodenal lesions in this patient was similar to that of the colonic lesions of ulcerative colitis.

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References

  1. Edwards FC, Truelove SC. The course and prognosis of ulcerative colitis. Gut 1964;5:1–22.

    Google Scholar 

  2. Rankin GB. Extraintestinal and systemic manifestations of inflammatory bowel disease. Med Clin North Am 1990;74:39–50.

    CAS  PubMed  Google Scholar 

  3. Lenaerts C, Roy CC, Vaillancourt M, et al. High incidence of upper gastrointestinal tract involvement in children with Crohn disease. Pediatrics 1989;83:777–781.

    CAS  PubMed  Google Scholar 

  4. Kirsner JB. Historical aspects of inflammatory bowel disease. J Clin Gastroenterol 1988;10:286–297.

    CAS  PubMed  Google Scholar 

  5. Hamilton ST, Morson BC. Ulcerative colitis pathology. In: Berk JEet al. (eds) Bockus gastroenterology. 4th ed. Philadelphia: Saunders, 1985;2139–2153.

    Google Scholar 

  6. Hirata I, Linda L, Austin BA, et al. Immunoelectron microscopic localization of HLA-DR antigen in control small intestine and colon and in inflammatory bowel disease. Dig Dis Sci 1986;31: 1317–1330.

    CAS  PubMed  Google Scholar 

  7. Jenkins RT, Ramage JK, Jones DB, et al. Small bowel and colonic permeability to 51Cr-EDTA in patients with active inflammatory bowel disease. Clin Invest Med 1988;11:151–155.

    CAS  PubMed  Google Scholar 

  8. Cheli R, Aste H. Inflammatory cell count and identification in chronic non-specific duodenitis. Endoscopy 1976;9:91–95.

    Google Scholar 

  9. Kreuning J, Bosman FT, Kuiper G, et al. Gastric and duodenal mucosa in healthy individuals. An endoscopic and histopathlogical study of 50 volunteers. J Clin Pathol 1978;31:69–77.

    CAS  PubMed  Google Scholar 

  10. Thompson JW, Bargen JA. Ulcerative duodenitis and chronic ulcerative colitis. Gastroenterology 1960;38:452–455.

    PubMed  Google Scholar 

  11. Igarashi M, Hirokado H, Suzuki H, et al. A case report of ulcerative colitis complicated with ulcerative duodenitis (in Japanese). J Jpn Soc Colo-proctol 1984;37:255–260.

    Google Scholar 

  12. Takamatsu M. An autopsy case of nonspecific ulcerative colitis associated with similar lesion in the stomach. Acta Pathol Jpn 1971;21:131–141.

    CAS  PubMed  Google Scholar 

  13. Manier JW, Reyes CN, Olsen TG. Ulcerative colitis and ulcerative gastritis. Am J Gastroenterol 1972;58:502–507.

    CAS  PubMed  Google Scholar 

  14. Hibi T, Aiso S, Yoshida T, et al. Anti-colon antibody and lymphocytophilic antibody in ulcerative colitis. Clin Exp Immunol 1982;49:75–80.

    CAS  PubMed  Google Scholar 

  15. Asakura H, Hibi T, Tsuchiya M. Differences in immunological aspects between ulcerative colitis and Crohn's disease. In: Tsuchiya M (ed) Frontiers of mucosal immunology. vol 1. Amsterdam: Elsevier Science 1991;37–44.

    Google Scholar 

  16. Breeling JL, Onderdonk AB.B. vulgatus outermembrane antigen associated with carrageenan-induced colitis in guinea pigs. Infect Immun 1988;56:1754–1759.

    CAS  PubMed  Google Scholar 

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Sasaki, M., Okada, K., Koyama, S. et al. Ulcerative colitis complicated by gastroduodenal lesions. J Gastroenterol 31, 585–589 (1996). https://doi.org/10.1007/BF02355062

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  • DOI: https://doi.org/10.1007/BF02355062

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