Summary
The presence of carnitine acetyl transferase (E.C.2.3.1.7) activity has been found for the first time in human platelets. The enzymic activity was measured by a radiometric method based on the separation of labelled acetylcarnitine and carnitine on a cation exchange column. Carnitine acetyl transferase activity closely paralleled the activity distribution of the mitochondrial marker carnitine palmitoyl-transferase. Contrary to the marker enzyme, human platelet carnitine acetyl-transferase is rather thermosensitive: 60% of its activity is lost after 10 min when kept at 37°C.
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Giret, M., Villanueva, V.R. On the presence of carnitine acetyl transferase in human platelets. Mol Cell Biochem 37, 65–69 (1981). https://doi.org/10.1007/BF02354929
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DOI: https://doi.org/10.1007/BF02354929