Advertisement

Hyperfine Interactions

, Volume 47, Issue 1–4, pp 329–342 | Cite as

Spin coupling in iron proteins and model complexes

  • E. Bill
  • X. -Q. Ding
  • H. Winkler
  • A. X. Trautwein
  • U. Gonser
Oral Contributions

Abstract

Transition metal ions are essential for the specific function of many biomolecules, like transport and activation of small molecules, electron transfer, etc. Their active sites contain (i) single paramagnetic or diamagnctic metal ions, or (ii) clusters of spin-coupled paramagnetic centers. Examples are for (i) hemoglobin or rubredoxin with one Fe, and for (ii) ferredoxins with [2Fe-2S] and [4Fe-4S] clusters, cytochrome c oxidasc containing Fe and Cu, or peroxidases with metal-radical pairs. Here, we present the results of our Mössbauer and EPR investigation of irondioxygen interaction in horse liver alcohol dehydrogenase (HLADH), of ironradical interaction in synthetic analogues of heme peroxidases and of iron-iron double exchange interaction in a synthetic ferric/ferrous mixed valence complex. We hope to demonstrate that the understanding of spin coupling can yield valuable insight in the relation between electronic structure and function of biological iron complexes.

Keywords

Exchange Interaction Alcohol Dehydrogenase Paramagnetic Center Synthetic Analogue Iron Complex 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. [1]
    C.-I. BrÄndein, H. Jörnvall, H. Eklund and B. Furugren, in:The Enzymes ed. P.D. Boyer, Vol. XI (Academic Press, New York, 1975) p. 103.Google Scholar
  2. [2]
    E. Bill, C. Haas, X.-Q. Ding, W. Maret, H. Winkler, A.X. Trautwein and M. Zeppezauer, Eur. J. Biochem. (accepted).Google Scholar
  3. [3]
    R.K. Scopes, FEBS Lett. 156(1983)303.CrossRefGoogle Scholar
  4. [4]
    C.E. Schulz, P.W. Devaney, H. Winkler, P.G. Debrunner, N. Doan, R. Chiang, R. Rutter and L.P. Hager, FEBS Lett. 103(1979)102.CrossRefGoogle Scholar
  5. [5]
    R. Rutter, L.P. Hager, H. Dhonau, M.P. Hendrich, M. Valentine and P.G. Debrunner, Biochem. 23(1984)6809.Google Scholar
  6. [6]
    C.E. Schulz, R. Rutter, J.T. Sage, P.G. Debrunner and L.P. Hager, Biochem. 23(1984)4743.Google Scholar
  7. [7]
    A. Gold, K. Jayaraj, P. Doppelt, R. Weiss, E. Bill, X.-Q. Ding, E.L. Bominaar, A.X. Trautwien and H. Winkler, Nouveau J. du Chimie (accepted).Google Scholar
  8. [8]
    E. Münck, V. Papaefthymiou, K.K. Surerus and J.-J. Girerd, in:Metals in Proteins, ed. L. Que (ACS Symposium Series), in press.Google Scholar
  9. [9]
    S. Drücke, P. Chaudhuri, K. Pohl, K. Wieghardt, X.-Q. Ding, E. Bill, A. Sawaryn, A.X. Trautwein, H. Winkler and S.J. Gurman, Chem. Comm. (accepted).Google Scholar
  10. [10]
    S.J. Gurman, N. Binsted and I. Ross, J. Phys. C17(1984)143; ibid. C19(1986)1845.ADSGoogle Scholar
  11. [11]
    The structure of [L2Cr2 Μ-OH)3]3+ is very similar: K. Wieghardt, P. Chaudhuri, B. Nuber and J. Weiss, Inorg. Chem. 21(1982)3086.Google Scholar
  12. [12]
    M. Zeppezauer, I. Andersson, H. Dietrich, M. Gerber, W. Maret, G. Schneider and H. Schneider-Bernlöhr, J. Mol. Cat. 23(1984)377.Google Scholar
  13. [13]
    H. Winkler, E. Bill, A.X. Trautwein, A. Kostikas, A. Simopoulos and A. Terzis, J. Chem. Phys. 89(1988)732.CrossRefADSGoogle Scholar
  14. [14]
    B. Boso, G. Lang, T.J. McMurry and J.T. Groves, J. Chem. Phys. 79(1983)1122.CrossRefADSGoogle Scholar
  15. [15]
    W.M. Reiff, in:Mössbauer Effect Methodology, ed. I.J. Gruverman and C.W. Seidel, Vol. 8 (Plenum Press, New York, 1973) p. 89.Google Scholar
  16. [16]
    N.N. Greenwood and T.C. Gibb, in:Mössbauer Spectroscopy (Chapman and Hall, London, 1971).Google Scholar
  17. [17]
    P.W. Anderson and H. Hasegawa, Phys. Rev. 100(1955)675.ADSGoogle Scholar

Copyright information

© J.C. Baltzer AG, Scientific Publishing Company 1989

Authors and Affiliations

  • E. Bill
    • 1
  • X. -Q. Ding
    • 1
  • H. Winkler
    • 1
  • A. X. Trautwein
    • 1
  • U. Gonser
    • 2
  1. 1.Institut für PhysikMedizinische UniversitÄtLübeckF.R.G.
  2. 2.Angewandte PhysikUniversitÄt des SaarlandesSaarbrückenF.R.G.

Personalised recommendations