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Sclerosing cholangitis

  • Review Article
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Journal of Hepato-Biliary-Pancreatic Surgery

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References

  1. MacCarty RL, LaRusso NF, Wiesner RH, Ludwig J (1983) Primary sclerosing cholangitis: Findings on cholangiography and pancreatography Radiology 149:39–44

    CAS  PubMed  Google Scholar 

  2. Chapman RW (1991) Aetiology and natural history of primary sclerosing cholangitis: A decade of progress? Gut 32:1433–1435

    CAS  PubMed  Google Scholar 

  3. Chapman RW, Varghese Z, Gaul R, Kokkinon N, Sherlock S (1983) Association of primary sclerosing cholangitis with HLA B8. Gut 24:38–41

    CAS  PubMed  Google Scholar 

  4. Schrumpf E, Fausa O, Gorre O, Doblong JH, Ritland S, Thorsby E (1982) HLA antigens and immunoregulatory T cells in ulcerative colitis associated with hepatobiliary disease. Scand J Gastroenterol 17:187–191

    CAS  PubMed  Google Scholar 

  5. Lillemoe KD, Pitt HA, Cameron JL (1990) Primary sclerosing cholangitis. Surg Clin North Am 70:1381–1402

    CAS  PubMed  Google Scholar 

  6. Chapman RW, Kelly PMA, Heryet A, Jewell DP, Fleming KA (1988) Expression of HLA-DR antigens on bile duct epithelium in primary sclerosing cholangitis. Gut 29:422–427

    CAS  PubMed  Google Scholar 

  7. Bodenheimer HCJ, LaRusso NF, Thayer WR, Charland C, Staples PJ, Ludwig, J (1983) Elevated circulating immune complexes in primary sclerosing cholangitis. Hepatology 3:150–154

    PubMed  Google Scholar 

  8. Snook JA, Chapman RW, Fleming KA, Jewell DP (1989) Anti-neutrophil nuclear antibody in ulcerative colitis, Crohn's disease and primary sclerosing cholangitis. Clin Exp Immunol 76:30–33

    CAS  PubMed  Google Scholar 

  9. Seibold F, Weber P, Klein R, Berg PA, Wiedmann KH (1992) Clinical significance of antibodies against neutrophils in patients with inflammatory bowel disease and primary sclerosing cholangitis. Gut 33:657–662

    CAS  PubMed  Google Scholar 

  10. Kemeny MM, Battifora H, Blayney DW, Cecchi G, Goldberg DA, Leong LA, Margolin KA, Terz JJ (1985) Selerosing cholangitis after continuous hepatic artery infusion of FUDR. Ann Surg 202:176–181

    CAS  PubMed  Google Scholar 

  11. Thompson HH, Pitt HA, Tompkins RK, Longmire WP Jr (1982) Primary sclerosing cholangitis: A heterogeneous disease. Ann Surg 196:127–136

    CAS  PubMed  Google Scholar 

  12. Cello JP (1989) Acquired immunodeficiency syndrome cholangiopathy: Spectrum of disease. Am J Med 86:539–546

    Article  CAS  PubMed  Google Scholar 

  13. Demetris AJ, Lasky S, Van Thiel DJ, Starzl TE, Dekker A (1985) Pathology of hepatic transplantation: A review of 62 adult allograft recipients immunosuppressed with a cyclosporine/steroid regimen. Am J Pathol 118:151–161

    CAS  PubMed  Google Scholar 

  14. Dickson ER, Murtaugh PA, Wiesner RH, Grambasch PM, Fleming TR, Ludwig J, LaRusso NF, Malinchoc M, Chapman RW, Kaplan MM, Maddrey WC, Williams R, Farrant M, Langworthy A (1992) Primary sclerosing cholangitis: Refinement validation of survival models. Gastroenterology 103: 1893–1901

    CAS  PubMed  Google Scholar 

  15. Wiesner RH, Porayko MK, Dickson ER, Gores GJ, LaRusso NF, Hay JE, Wahlstrom HE, Krom RAF (1992) Selection and timing of liver transplantation in primary biliary cirrhosis and primary sclerosing cholangitis. Hepatology 16:1290–1299

    Article  CAS  PubMed  Google Scholar 

  16. Cameron JL, Pitt HA, Zinner MJ, Herlong JF, Kaufman SL, Boitnott JK, Coleman J (1988) Resection of hepatic duct bifurcation and transhepatic stenting for sclerosing cholangitis, Ann Surg 207:614–622

    CAS  PubMed  Google Scholar 

  17. Chapman RW, Marborgh BA, Rhodes JM, Summerfield JA, Dick R, Scheuer PJ, Sherlock S (1980) Primary sclerosing cholangitis: A review of its clinical features, cholangiography and hepatic histology Gut 21:870–877

    CAS  PubMed  Google Scholar 

  18. Ludwig J, Barham SS, LaRusso NF, Elveback LR, Wiesner RH, McCall JT, (1981) Morphologic features of chronic hepatitis associated with primary sclerosing cholangitis and chronic ulcerative colitis Hepatology 1:632–640

    CAS  PubMed  Google Scholar 

  19. Helzberg JH, Petersen JM, Boyer JL (1987) Improved survival with primary sclerosing cholangitis: A review of clinicopathologic features and comparison of symptomatic and asymptomatic patients, Gastroenterology 92: 1869–1875

    CAS  PubMed  Google Scholar 

  20. Fausa O, Schrumpf E, Elgjo K (1991) Relationship of inflammatory bowel disease and primary sclerosing cholangitis. Semin Liver Dis 11:31–39

    CAS  PubMed  Google Scholar 

  21. Aadland E, Schrumpf E, Fausa O, Elgjo K, Heilo A, Aakhus T, Gjone E (1987) Primary sclerosing cholangitis: A long-term follow-up study. Scand J Gastroenterol 22:655–664

    CAS  PubMed  Google Scholar 

  22. Rabinovitz M, Gavaler JS, Schade RR, Dindzans VJ, Chien MC, Van Thiel H (1990) Does primary sclerosing cholangitis occurring in association with inflammatory bowel disease differ from that occurring in the absence of inflammatory bowel disease? A study of 66 subjects. Hepatology 11:7–11

    CAS  PubMed  Google Scholar 

  23. Broomé U, Lindberg G, Löfberg R (1992) Primary sclerosing cholangitis in ulcerative colitis: A risk factor for the development of dysplasia and DNA aneuploidy? Gastroenterology 102: 1877–1880

    PubMed  Google Scholar 

  24. Rosen CB, Nagorney DM (1991) Cholangiocarcinoma complicating primary sclerosing cholangitis. Semin Liver Dis 11:26–30

    CAS  PubMed  Google Scholar 

  25. Cangemi JR, Wiesner RH, Beaver SJ, Ludwig J, MacCarty RL, Dozois RR, Zinsmeister AR, LaRusso NF (1989) Effect of proctocolectomy for chronic ulcerative colitis on the natural history of primary sclerosing cholangitis. Gastroenterology 96:790–794

    CAS  PubMed  Google Scholar 

  26. Kartheuser AH, Dozois RR, Wiesner RH, LaRusso NF, Illstrup DM, Schleck CD (1993) Complications and risk factors after ileal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitis. Ann Surg 217:314–320

    CAS  PubMed  Google Scholar 

  27. Abu-Elmagd KM, Selby R, Iwatsuki S, Fung J, Tzakis A, Todo S, Demetris AJ, Baddour N, Irish W, Van Thiel DH, Starzl TE (1993) Cholangiocarcinoma and sclerosing cholangitis: Clinical characteristics and effect on survival after liver transplantation. Transplant Proc 25:1124–1128

    CAS  PubMed  Google Scholar 

  28. Farges O, Malassagne B, Sebaugh M, Bismuth H (1995) Primary sclerosing cholangitis: Liver transplantation or biliary surgery. Surgery 117:146–155

    CAS  PubMed  Google Scholar 

  29. Rosen CR, Nagorney DM, Wiesner RH, Coffey RJ, LaRusso NF (1991) Cholangiocarcinoma complicating primary sclerosing cholangitis. Ann Surg 213:21–25

    CAS  PubMed  Google Scholar 

  30. Cameron JL, Gayler BW, Sanfey H, Milligan F, Kaufman S, Maddrey WC, Herlong HF (1984) Sclerosing cholangitis: Anatomical distribution of obstructive lesions. Ann Surg 200:54–60

    CAS  PubMed  Google Scholar 

  31. Ramage JK, Donaghy A, Farrant JM, Iorns R, Williams R (1995) Serum tumor markers for the diagnosis of cholangiocarcinoma in primary sclerosing cholangitis. Gastroenterology 108:865–869

    Article  CAS  PubMed  Google Scholar 

  32. Nichols JC, Gores GJ, LaRusso NF, Wiesner RH, Nagorney DM, Ritts RE Jr (1993) Diagnostic role of serum CA 19-9 for cholangiocarcinoma in patients with primary sclerosing cholangitis. Mayo Clin Proc 68:874–879

    CAS  PubMed  Google Scholar 

  33. Nakeeb A, Lipsett PA, Lillemoe KD, Fox-Talbot MK, Coleman J, Cameron JL, Pitt HA (1996) Biliary CEA levels are a marker for cholangiocarcinoma. Am J Surg 171:147–153

    Article  CAS  PubMed  Google Scholar 

  34. Wiesner RH, Grambsch PM, Dickson ER, Ludwig J, MacCarty RL, Hunter EB, Fleming TR, Fisher LD, Beaver SJ, LaRusso NF (1989) Primary sclerosing cholangitis: Natural history, prognostic factors, and survival analysis. Hepatology 10:430–436

    CAS  PubMed  Google Scholar 

  35. Porayko MK, Wiesner RH, LaRusso NF, Ludwig J, MacCarty RL, Steiner BL, Twomey CK, Zinsmeister AR (1990) Patients with asymptomatic primary sclerosing cholangitis frequently have progressive disease. Gastroenterology 98:1594–1602

    CAS  PubMed  Google Scholar 

  36. Farrant JM, Hayllar KM, Wilkinson ML, Karani J, Portmann BC, Westaby D, Williams R (1991) Natural history and prognostic variables in primary sclerosing cholangitis. Gastroenterology 100:1710–1717

    CAS  PubMed  Google Scholar 

  37. Muller EL, Miyamoto T, Pitt HA, Longmire WP Jr (1985) Anatomy of the choledochopancreatic duct junction in primary sclerosing cholangitis. Surgery 97:21–26

    CAS  PubMed  Google Scholar 

  38. Kaplan MM (1991) Medical approaches to primary sclerosing cholangitis. Semin Liver Dis 11:56–63

    CAS  PubMed  Google Scholar 

  39. Wiesner RH, Steiner B, LaRusso NF, Lindor KD, Baldus WP (1991) A controlled trial evaluating cyclosporine in the treatment of primary sclerosing cholangitis (abstract). Hepatology 14:63

    Article  Google Scholar 

  40. O'Brien CB, Senior JR, Arora-Mirchandani R, Batta AK, Salen G (1991) Ursodeoxycholic acid for the treatment of primary sclerosing cholangitis: A 30-month pilot study. Hepatology 14:838–847

    PubMed  Google Scholar 

  41. Kaplan MM, Arora S, Pincus SH (1987) Primary sclerosing cholangitis and low-dose oral pulse methotrexate therapy. Ann Intern Med 106:231–235

    CAS  PubMed  Google Scholar 

  42. Beuers U, Spenger U, Kruis W, Aydemir U, Wiebecke B, Heldwein W (1992) Ursodeoxycholic acid for treatment of primary sclerosing cholangitis: A placebo-controlled trial. Hepatology 16:707–714

    CAS  PubMed  Google Scholar 

  43. Knox T, Kaplan MM (1994) A double-blind controlled trial of oral-pulse methotrexate therapy in the treatment of primary sclerosing cholangitis. Gastroenterology 106:494–499

    CAS  PubMed  Google Scholar 

  44. Lee JG, Schutz SM, England RE, Leung JW, Cotton PB (1995) Endoscopic therapy of sclerosing cholangitis. Hepatology 21: 661–667

    CAS  PubMed  Google Scholar 

  45. Johnson GK, Geenen JE, Venu RP, Schmalz MJ, Hogan WJ (1991) Endoscopic treatment of biliary tract strictures in sclerosing cholangitis: A larger series and recommendations for treatment. Gastrointest Endosc 37:38–43

    CAS  PubMed  Google Scholar 

  46. Mueller PR, vanSonnenberg E, Ferruci JT, Weyman PJ, Butch RJ, Malt RA, Burhenne HJ (1986) Biliary stricture dilatation: Multicenter review of clinical management of 73 patients. Radiology 160:17–22

    CAS  PubMed  Google Scholar 

  47. Cameron JL, Gayler BW, Herlong JF, Maddrey WC (1983) Sclerosing cholangitis: Biliary reconstruction with Silastic transhepatic stents. Surgery 94:324–330

    CAS  PubMed  Google Scholar 

  48. Ahrendt SA, Pitt HA, Kalloo AN, Venbrux A, Klein AS, Herlong JF, Coleman J, Lillemoe KD, Cameron JL (1995) Primary sclerosing cholangitis: Resect, dilate, or transplant (abstract)?, Gastroenterology 108:1211

    Google Scholar 

  49. Ahrendt SA, Pitt HA, Kalloo AN, Venbrux A, Klein AS, Herlong JF, Coleman J, Lillemoe KD, Cameron JL (1995) Management of primary sclerosing cholangitis in the 1990s (abstract). Hepatology 22:107

    Google Scholar 

  50. Cameron JL (1990) Atlas of surgery, vol 1 B.C. Decker, Philadelphia, pp 94–115

    Google Scholar 

  51. Marsh JW, Iwatsuki S, Makowka L, Esquirel CO, Gordon RD, Todo S, Tsakis A, Miller C, Van Thiel D, Starzl TE (1988) Orthotopic liver transplantation for primary sclerosing cholangitis. Ann Surg 207:21–25

    PubMed  Google Scholar 

  52. Abu-Elmagd KM, Malinchoc M, Dickson ER, Fung JJ, Murtaugh PA, Langworthy AL, Demetris AJ, Krom RAF, Van Thiel DJ, Starzl TE (1993) Efficacy of hepatic transplantation in patients with primary sclerosing cholangitis. Surg Gynecol Obstet 177:335–344

    CAS  PubMed  Google Scholar 

  53. Narumi S, Roberts JP, Emond JC, Lake J, Ascher NL (1995) Liver transplantation for sclerosing cholangitis. Hepatology 22:451–457

    Article  CAS  PubMed  Google Scholar 

  54. Strasser S, Sheil AGR, Gallagher ND, Waugh R, McCaughan GW (1993) Liver transplantation for primary sclerosing cholangitis versus primary biliary cirrhosis: A comparison of complications and outcome. J Gastroenterol Hepatol 8:238–243

    CAS  PubMed  Google Scholar 

  55. Miros M, Kerlin P, Walker N, Harper J, Lynch S, Strong R (1991) Predieting cholangiocarcinoma in patients with primary sclerosing cholangitis before transplantation. Gut 32:1369–1373

    CAS  PubMed  Google Scholar 

  56. Shaked A, Colonna JO, Goldstein L, Busuttil RW (1992) The interrelation between sclerosing cholangitis and ulcerative colitis in patients undergoing liver transplantation. Ann Surg 215:598–605

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Surgery, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, 21287, Baltimore, MD, USA

    Steven A. Ahrendt & Henry A. Pitt

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  1. Steven A. Ahrendt
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  2. Henry A. Pitt
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Ahrendt, S.A., Pitt, H.A. Sclerosing cholangitis. J Hep Bil Pancr Surg 3, 431–441 (1996). https://doi.org/10.1007/BF02349788

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  • DOI: https://doi.org/10.1007/BF02349788

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