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Study on intracellular calcium localization by potassium antimonate technique in rabbit VX2 carcinoma

  • Workshop II: Analytical Electron Microscopy
  • Workshop II-4
  • Published:
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Abstract

It is well known that a rabbit having VX2 carcinoma, which derived from virus-induced papillomas, shows hypercalcemia from the early stage of its growth. Ultrathin sections of the VX2 carcinoma were examined for the evaluation of calcium localization using a potassium antimonate technique and X-ray microanalysis. The calcium antimonate complex was shown to be most prevalent in the euchromatin and mitochondria.

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References

  1. Campbell, A. K.: The investigation of intracellular Ca2+ as regulator. In: Intracellular Calcium (Campbell, A.K. ed.), p. 23–84, John Wiley & Sons Ltd., Chichester, 1983.

    Google Scholar 

  2. Macra, I.G.: Oncogenes, ions and phospholipid.Am. J. Physiol. 248, C3–11 (1985).

    Google Scholar 

  3. Yoneda, T., Kitamura, M., Ogawa, T., andSakuda, M.: Control of VX2 carcinoma cell growth in culture by calcium, calmodulin, and prostaglandins.Cancer Res. 45, 398–405 (1985).

    CAS  PubMed  Google Scholar 

  4. Meyer, H.: Increased intracellular calcium: from hypertension to cancer.J. Hypertens. 5, 53–54 (1987).

    Google Scholar 

  5. Komnick, H.: Elektronemikroskopische Lokalisation von Na und Cl in zellen und Geweben.Protoplasma,55, 414–418 (1962).

    Article  CAS  Google Scholar 

  6. Appleton, J. andMorris, D.C.: An ultrastructural investigation of the role of the odontoblast in matrix calcification using the potassium pyroantimonate osmium for calcium localization.Arch. Biol. 24, 467–475 (1979).

    CAS  Google Scholar 

  7. Sampson, H. W., Bowers, D. E. andPiscopo, I.: Calcium and parotid gland secretion; a cytochemical study.J. Anat. 136, 573–583 (1983).

    CAS  PubMed  Google Scholar 

  8. Wick, S.M. andHepler, P.: Selective localization of intracellular Ca with potassium antimonate.J. Histochem. Cytochem. 30, 1190–1204 (1982).

    CAS  PubMed  Google Scholar 

  9. Tander, C.T., Libanati, C.M. andSanchis, C.A.: The intracellular localization of inorganic cations with potassium pyroantimonate.J. Cell Biol. 45, 355–366 (1980).

    Google Scholar 

  10. Timm, B.G. andChandler, T.A.: Endogenous elements in the prostate; X-ray microanalytical study of freeze-dried frozen sections and histochemical localization of zinc by potassium pyroantimonate.Histochem. J. 16, 733–754 (1984).

    Google Scholar 

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Authors and Affiliations

  1. Second Department of Maxillofacial and Oral Surgery, School of Dentistry, Nagasaki University, 1-7, Sakamotomachi, 852, Nagasaki, Japan

    Akira Kitamura & Tsugio Inokuchi

  2. Second Department of Oral Anatomy, School of Dentistry, Nagasaki University, 1-7, Sakamotomachi, 852, Nagasaki, Japan

    Kunio Takano

Authors
  1. Akira Kitamura
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  2. Kunio Takano
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  3. Tsugio Inokuchi
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Kitamura, A., Takano, K. & Inokuchi, T. Study on intracellular calcium localization by potassium antimonate technique in rabbit VX2 carcinoma. Med Electron Microsc 27, 333–336 (1994). https://doi.org/10.1007/BF02349689

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  • DOI: https://doi.org/10.1007/BF02349689

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