Journal of Gastroenterology

, Volume 30, Issue 6, pp 779–782 | Cite as

Mucinous cystadenoma of appendix concomitant with perityphlic granuloma

  • Takafumi Sato
  • Tadashi Ueda
  • Hiroshi Kon
  • Soroku Yagihashi
  • Hitoshi Kotanagi
Case Reports


We describe a case of mucinous cystadenoma of the appendix with perityphlic granuloma. The patient developed a hard palpable mass in the right lower quadrant and barium enema inducted irregular bowel wall at the cecum. Based on a preoperative diagnosis of carcinoma of the appendix, we performed a laparotomy. On operation, we found a tumor mass in the region of the appendix; the mass adhered strongly to the retroperitoneum and cecum. Right hemicolectomy was carried out on a diagnosis of carcinoma of the appendix. Microscopic examination revealed mucinous cystadenoma of the appendix with perityphlic granuloma. Mucinous cystadenoma in the appendix is a rare tumor. In this patient, the tumor was accompanied by granuloma formation in adjacent tissues because of mucin expelled from the appendix. This case emphasizes that granuloma formation can make of difficult to differentiate mucinous cystadenoma in the appendix from cancer.

Key words

mucinous cystadenoma appendix perityphlic granuloma 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Higa E, Rosai J, Pizzimbono CA, Wise L. Mucosal hyperplasia, mucinous cystadenoma, and mucinous cystadenocarcinoma of the appendix. A re-evaluation of appendiceal “mucocele” Cancer 1973;32:1525–1541.PubMedGoogle Scholar
  2. 2.
    Aho A, Heinomen R, Lauren P, Benign, and malignant mucocele of the appendix: Histologic types and prognosis. Acta Chir Scand 1973;139:392–400.PubMedGoogle Scholar
  3. 3.
    Dachman AH, Lichtenstein JE, Friedman AC. Mucocele of the appendix and pseudomyxoma peritonei, AJR 1985;144:923–929.PubMedGoogle Scholar
  4. 4.
    Isaacs KL, Warshauer DM. Mucocele of the appendix: Computed tomographic, endoscopic, and pathologic correction. Am J Gastroenterol 1992;87:787–789.PubMedGoogle Scholar
  5. 5.
    Yoshida Y, Kamegawa T, Sugio K. Mucocele of the appendix accurately diagnosed using computer tomography. Clin Imaging 1990;14:61–63.CrossRefPubMedGoogle Scholar
  6. 6.
    Koster LH. Symptomatic mucocele of the appendix diagnosed preoperatively. Am J Surg 1974;127:582–584.CrossRefPubMedGoogle Scholar
  7. 7.
    Horgan J, Chow P, Richter J, et al. CT and sonography in the recognition of mucocele of the appendix. AJR 1984;43:959–962.Google Scholar
  8. 8.
    Adolfsson G. Benign and malignant tumors of the appendix. Acta Chir Scand 1974;140:151–155.PubMedGoogle Scholar
  9. 9.
    Woodruff R, McDonald JR. Benign and malignant cystic tumors of the appendix. Surg Gynecol Obstet 1940;71:750–755.Google Scholar
  10. 10.
    Gibbs NM. Mucinous cystadenoma and cystadenocarcinoma of the vermiform appendix with particular reference to mucocele and pseudomyxoma peritonei. J Clin Pathol 1973;26:413–416.PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • Takafumi Sato
    • 1
  • Tadashi Ueda
    • 1
  • Hiroshi Kon
    • 1
  • Soroku Yagihashi
    • 2
  • Hitoshi Kotanagi
    • 3
  1. 1.Department of SurgeryHokushu Chuo HospitalAkitaJapan
  2. 2.School of Medicine, Department of PathologyHirosaki UniversityAomoriJapan
  3. 3.School of Medicine, Department of SurgeryAkita UniversityAkitaJapan

Personalised recommendations