Abstract
Using video microscopy in 225 resected stomachs we detected 32 minute solitary lesions of intestinal metaplasia histologically. The magnified features of the minute lesions showed a characteristic appearance and were classified into three types: meshlike (type A), villoid (type B), and tubular (type C). All the lesions classified as type A exhibited the incomplete type of intestinal metaplasia according to the results of histopathological and/or histochemical examination. In contrast, most lesions classified as type B exhibited the complete type of intestinal metaplasia. We concluded that intentional detection of minute lesions in resected stomachs by video microscopy is simple and useful, especially in cases of minute lesions <5 mm in diameter. Moreover, our findings demonstrate that the minute intestinal metaplastic lesions have morphological characteristics based on which they can be classified into three types of lesions. These morphological characteristics correlate with their histopathological findings.
Similar content being viewed by others
References
Oohara T, Tohma H, Takezoe K, et al. Minute gastric cancers less than 5 mm in diameter. Cancer 1982;50:801–810.
Rubio CA, Kato Y, Sugano H, et al. Intestinal metaplasia of the stomach in Swedish and Japanese patients without ulcers or carcinoma. Jpn J Cancer Res 1987;78:467–472.
Mukawa K, Nakamura T, Nakano G, et al. Histopathogenesis of intestinal metaplasia: Minute lesions of intestinal metaplasia in ulcerated stomachs. J Clip Pathol 1987;40:13–18.
Kawachi T, Kogure K, Tanaka N, et al. Studies of intestinal metaplasia in the gastric mucosa by detection of disaccharidases with Tes-Tape. J Natl Cancer Inst 1974;53:19–30.
Suzuki S, Suzuki H, Endo M, et al. Encoscopic diagnosis of early cancer and intestinal metaplasia of the stomach by dyeing. Intern Surg 1973;58:639–642.
Satake S, Kino I. A study of intestinal metaplasia of the human stomach, with special reference to goblet cell metaplasia (in Japanese with English abstract). I to Cho (Stomach and Intestine) 1982;17:1029–1034.
Kobayashi T, Kimura T, Harada Y, et al. Experience of magnifying observation for gastric mucosal surface using video microscope (in Japanese with English abstract). Gastroenterol Endosc 1993;35:596–599.
Kobayashi T, Kimura T, Harada Y, et al. A case of IIb type minute gastric cancer detected by video microscope (in Japanese with English abstract). Shokaki naishikyo (Endose Digest) 1993;5:121–124.
Yoshii T. Comparative study of chronic gastritis with dissecting microscopic findings of stained stomach and its histological findings. Application to endoscopic diagnosis (in Japanese). Shokaki naishikyo no Shinpo (Progr Dig Endosc) 1976;9:49–53.
Filipe MI. Mucins in the human gastrointestinal epithelium; a review. Invest Cell Pathol 1979;2:195–216.
Kobayashi T, Kimura T, Harada Y, et al. Application of a video microscope to observe the gastric mucosal surface, especially in early gastric cancer. Dig Endosc 1994;6:195–200.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kobayashi, T., Kimura, T., Harada, Y. et al. Detection of minute intestinal metaplastic lesions by video microscopy. J Gastroenterol 29, 710–714 (1994). https://doi.org/10.1007/BF02349275
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02349275