Skip to main content
Log in

Variously-formed inclusions in the rough endoplasmic reticulum of plasma cells in the human oviduct mucosa

  • Published:
Medical Electron Microscopy Aims and scope Submit manuscript

Abstract

Human oviducts, obtained from 60 women having undergone total hysterectomy due to diseases of the uterus or ovary, were studied for cyclic changes by electron microscopy. In the studies, plasma cells were frequently observed in the lamina propria of the oviductal mucosa. Russell bodies were occasionally encountered in the plasma cells. In the oviduct mucosa obtained from a patient with cervical carcinoma, a plasma cell contained C-shaped or worm-like structures in an extensively-distended cisterna of the rER. These structures were morphologically quite similar to type A curvilinear bodies in lysosomes of certain lysosomal diseases. Additionally, intracisternal tubules were noted in slightly dilated cisternae of other rER. The origins and functional significance of curvilinear inclusions and intracisternal tubules in the plasma cell remain obscure.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Ghadially, F.N.: Ultrastructural Pathology of the Cell and Matrix, Vol. 1, 2, 3rd ed., Butter worths, London, 1988.

    Google Scholar 

  2. Farquhar, M.G. andRinehart, J.F.: Electron microscopic studies of the anterior pituitary gland of castrate rats.Endocrinology,54, 516–541 (1954).

    CAS  PubMed  Google Scholar 

  3. Palade, G.E.: Intracisternal granules in the exocrine cells of the pancreas.J. Biophys. Biochem. Cytol. 2, 417–422 (1956).

    CAS  PubMed  Google Scholar 

  4. Kostianovsky, M., andGhadially, F.N.: Intracisternal tubules in a case of chronic lymphocytic leukemia.J. Submicrosc. Cytol. 19, 509–514 (1987).

    CAS  PubMed  Google Scholar 

  5. Begin, L.R., Osborne, B.M. andMackay, B.: Monocytic leukemia with cutaneous involvement: ultrastructural observations on unusual cytoplasmic complexes.Ultrastruct. Pathol. 2, 11–18 (1981).

    Google Scholar 

  6. Behnke, O. andMoe, H.: An electron microscope study of mature and differentiating Paneth cells in the rat, especially of their endoplasmic reticulum and lysosomes.J. Cell Biol. 22, 633–652 (1964).

    Article  CAS  PubMed  Google Scholar 

  7. Maynard, J.A., Cooper, R.R., andPonseti, I.V.: A unique rough surfaced endoplasmic reticulum inclusion in pseudochondroplasia.Lab. Invest. 26, 40–44 (1972).

    CAS  PubMed  Google Scholar 

  8. Russell, W.: An address on a characteristic organism of cancer.Br. Med. J. 2, 1356–1360 (1890).

    Google Scholar 

  9. Welsh, R.: Electron microscopic localization of Russell bodies in the human plasma cell.Blood,16, 1307–1312 (1960).

    CAS  PubMed  Google Scholar 

  10. El-Okada, M., Hyeh, Y., Xie, S.S. andHsu, S.M.: Russell bodies consist of heterogeneous glycoproteins in B-cell lymphoma.Am. J. Clin. Pathol. 97, 866–871 (1992).

    Google Scholar 

  11. Fawcett, D.W.: The Cell, 2nd ed., W.B. Saunders, Philadelphia, 1981.

    Google Scholar 

  12. Fawcett, D.W.: Bloom and Fawcett, A Text Book of Histology, 12th ed., Chapman & Hall, New York, 1994.

    Google Scholar 

  13. Lee, G.R., Bithell, T.C., Foerster, J., Athens, J.W. andLukens, J.N.: Wintrobe's Clinical Hematology, Vol. 1, 9th ed., Lea & Febiger, Philadelphia, 1993.

    Google Scholar 

  14. Zucker-Franklin, D., Greaves, M.F., Grossi, C.E. andMarmont, A.M.: Atlas of Blood Cells, Function and Pathology, Vol. 2, 2nd ed., Lea & Febiger, Philadelphia, 1988.

    Google Scholar 

  15. Monma, N., Satodate, R., Suzuki, H. andUjhe, T.: Cerold-lipofuscinosis, report of two autopsy cases.Acta Pathol. Jpn. 38, 1191–1203 (1988).

    CAS  PubMed  Google Scholar 

  16. Moser, H.W., Moser, A.B., Chen, W.W. andSchrem, A.W.: Ceramidase deficiency: farber lipogranulomatosis.In: The Metabolic Basis of Inherited Disease (Scriver, C.R., Beaudet, A.L., Sly, W.S. andValle, D. ed.), p. 1645–1654, McGraw-Hill, New York, 1989.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hagiwara, H., Shibasaki, S. & Ohwada, N. Variously-formed inclusions in the rough endoplasmic reticulum of plasma cells in the human oviduct mucosa. Med Electron Microsc 28, 181–186 (1995). https://doi.org/10.1007/BF02347961

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02347961

Key words

Navigation