Abstract
Human oviducts, obtained from 60 women having undergone total hysterectomy due to diseases of the uterus or ovary, were studied for cyclic changes by electron microscopy. In the studies, plasma cells were frequently observed in the lamina propria of the oviductal mucosa. Russell bodies were occasionally encountered in the plasma cells. In the oviduct mucosa obtained from a patient with cervical carcinoma, a plasma cell contained C-shaped or worm-like structures in an extensively-distended cisterna of the rER. These structures were morphologically quite similar to type A curvilinear bodies in lysosomes of certain lysosomal diseases. Additionally, intracisternal tubules were noted in slightly dilated cisternae of other rER. The origins and functional significance of curvilinear inclusions and intracisternal tubules in the plasma cell remain obscure.
Similar content being viewed by others
References
Ghadially, F.N.: Ultrastructural Pathology of the Cell and Matrix, Vol. 1, 2, 3rd ed., Butter worths, London, 1988.
Farquhar, M.G. andRinehart, J.F.: Electron microscopic studies of the anterior pituitary gland of castrate rats.Endocrinology,54, 516–541 (1954).
Palade, G.E.: Intracisternal granules in the exocrine cells of the pancreas.J. Biophys. Biochem. Cytol. 2, 417–422 (1956).
Kostianovsky, M., andGhadially, F.N.: Intracisternal tubules in a case of chronic lymphocytic leukemia.J. Submicrosc. Cytol. 19, 509–514 (1987).
Begin, L.R., Osborne, B.M. andMackay, B.: Monocytic leukemia with cutaneous involvement: ultrastructural observations on unusual cytoplasmic complexes.Ultrastruct. Pathol. 2, 11–18 (1981).
Behnke, O. andMoe, H.: An electron microscope study of mature and differentiating Paneth cells in the rat, especially of their endoplasmic reticulum and lysosomes.J. Cell Biol. 22, 633–652 (1964).
Maynard, J.A., Cooper, R.R., andPonseti, I.V.: A unique rough surfaced endoplasmic reticulum inclusion in pseudochondroplasia.Lab. Invest. 26, 40–44 (1972).
Russell, W.: An address on a characteristic organism of cancer.Br. Med. J. 2, 1356–1360 (1890).
Welsh, R.: Electron microscopic localization of Russell bodies in the human plasma cell.Blood,16, 1307–1312 (1960).
El-Okada, M., Hyeh, Y., Xie, S.S. andHsu, S.M.: Russell bodies consist of heterogeneous glycoproteins in B-cell lymphoma.Am. J. Clin. Pathol. 97, 866–871 (1992).
Fawcett, D.W.: The Cell, 2nd ed., W.B. Saunders, Philadelphia, 1981.
Fawcett, D.W.: Bloom and Fawcett, A Text Book of Histology, 12th ed., Chapman & Hall, New York, 1994.
Lee, G.R., Bithell, T.C., Foerster, J., Athens, J.W. andLukens, J.N.: Wintrobe's Clinical Hematology, Vol. 1, 9th ed., Lea & Febiger, Philadelphia, 1993.
Zucker-Franklin, D., Greaves, M.F., Grossi, C.E. andMarmont, A.M.: Atlas of Blood Cells, Function and Pathology, Vol. 2, 2nd ed., Lea & Febiger, Philadelphia, 1988.
Monma, N., Satodate, R., Suzuki, H. andUjhe, T.: Cerold-lipofuscinosis, report of two autopsy cases.Acta Pathol. Jpn. 38, 1191–1203 (1988).
Moser, H.W., Moser, A.B., Chen, W.W. andSchrem, A.W.: Ceramidase deficiency: farber lipogranulomatosis.In: The Metabolic Basis of Inherited Disease (Scriver, C.R., Beaudet, A.L., Sly, W.S. andValle, D. ed.), p. 1645–1654, McGraw-Hill, New York, 1989.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hagiwara, H., Shibasaki, S. & Ohwada, N. Variously-formed inclusions in the rough endoplasmic reticulum of plasma cells in the human oviduct mucosa. Med Electron Microsc 28, 181–186 (1995). https://doi.org/10.1007/BF02347961
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02347961