Skip to main content

Advertisement

Log in

Resected case of carcinoid tumor of the liver metastatic from the breast

  • Case Reports
  • Published:
Journal of Gastroenterology Aims and scope Submit manuscript

Abstract

Carcinoid tumor metastatic to the liver from the breast is very unusual. We report a rare case in which the patient underwent curative resection for metastatic lesions to the liver. She had undergone a modified radical mastectomy more than 1 year previously for breast cancer. Recently, it was found that plasma levels of carcinoembryonic antigen (CEA) was elevated, and abdominal ultrasonography detected a liver tumor. The patient underwent a lateral segmentectomy of the liver, resulting in normalization of plasma CEA levels. The resected specimen was diagnosed as carcinoid tumor by histological, immunohistochemical, and ultrastructural microscopic studies. Re-examination of the breast tumor proved it to be the primary carcinoid.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Cubilla AL, Woodruff JM. Primary carcinoid tumor of the breast. A report of eight patients. Am J Surg Pathol 1977;1: 283–292.

    Google Scholar 

  2. Giacchi R, Sebastiani M, Lungarotti F. The so-called carcinoid tumors of the breast. It J Surg Sci 1986;16:249–253.

    CAS  Google Scholar 

  3. MacGillivray DC, Synder DA, Drucker W, et al. Carcinoid tumors: The relationship between clinical presentation and the extent of disease. Surgery 1991;110:68–72.

    CAS  PubMed  Google Scholar 

  4. Andreola S, DiRe E, Merson M, et al. Immunohistochemical study of ten cases of argyrophilic carcinoma (carcinoid) of the breast. Tumori 1988;74:295–302.

    CAS  PubMed  Google Scholar 

  5. Ipponsugi S, Koga T, Matsuo T, et al. A case of carcinoid tumor of the breast with bone metastasis. Jpn J Breast Cancer 1993;8:433–438.

    Google Scholar 

  6. Kaneko H, Sumida T, Sekiya M, et al. A breast carcinoid tumor with special reference to ultrastructural study. Acta Pathol Jpn 1982;32:327–332.

    CAS  PubMed  Google Scholar 

  7. Wang C-Y, Chen A, Tseng H-H, et al. Carcinoid tumor localized in the liver. Report of two cases: Immunohistochemical and ultrastructural studies. Chin Med J [Engl] 1992;49:365–372.

    CAS  Google Scholar 

  8. Pearse AGE, Polak JM. Endocrine tumors of neural crest origin: Neulophomas, apudomas, and the APUD concept. Med Biol 1974;52:3–18.

    CAS  PubMed  Google Scholar 

  9. Van Laarhoven HAJ, Gratama S, Wereldsma JCJ. Neuroendocrine carcinoid tumours of the breast: A variant of carcinoma with neuroendocrine differentiation. J Surg Oncol 1991; 46:125–132.

    PubMed  Google Scholar 

  10. Andreola S, Lombardi L, Audisio RA, et al. A clinicopathologic study of primary hepatic carcinoid tumors. Cancer 1990; 65:1211–1218.

    CAS  PubMed  Google Scholar 

  11. Sariola H, Lehtonen E, Saxén E. Breast tumors with a solid and uniform carcinoid pattern. Ultrastructural and immunohistochemical study of two cases. Pathol Res Pract 1985;178:405–411.

    Google Scholar 

  12. Taxy JB, Tischler AS, Insalaco SJ, et al. “Carcinoid” tumor of the breast. A variant of conventional breast cancer? Hum Pathol 1981;12:170–179.

    CAS  PubMed  Google Scholar 

  13. Rasmussen BB, Rose C, Thorpe SM, et al. Argyrophilic cells in 202 human mucinous breast carcinomas. Relation to histopathologic and clinical factors. Am J Clin Pathol 1985;84:737–740.

    CAS  PubMed  Google Scholar 

  14. Bussolati G, Gugliotta P, Sapino A, et al. Chromograninreactive endocrine cells in argyrophilic carcinomas (“carcinod”) and normal tissue of the breast. Am J Pathol 1985;120:186–192.

    CAS  PubMed  Google Scholar 

  15. Kurosumi M, Nomoto C, Suemasu K, et al. Argyrophilic carcinoma “carcinoid tumor” of the breast: Case report with electron microscopic and immunohistochemical investigations. Jpn J Clin Oncol 1989;19:397–401.

    CAS  PubMed  Google Scholar 

  16. Martin JK, Moertel CG, Adson MA, et al. Surgical treatment of functioning metastatic carcinoid tumors. Arch Surg 1983;118: 537–542.

    PubMed  Google Scholar 

  17. Dawes L, Schulte WJ, Condon RE. Carcinoid tumors. Arch Surg 1984;119:375–378.

    CAS  PubMed  Google Scholar 

  18. Thompson GB, van Heerden JA, Martin JKJr, et al. Carcinoid tumors of the gastrointestinal tract: Presentation, management, and prognosis. Surgery 1985;98:1054–1063.

    CAS  PubMed  Google Scholar 

  19. Odurny A, Birch SJ. Hepatic arterial embolisation in patients with metastatic carcinoid tumours. Clin Radiol 1985;36:597–602.

    Article  CAS  PubMed  Google Scholar 

  20. Zarrilli L, Marzano LA, Porcelli A, et al. The surgical management of carcinoid tumors. J Nucl Biol Med 1991;35:341–342.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Imamura, M., Yamauchi, H. & Namiki, T. Resected case of carcinoid tumor of the liver metastatic from the breast. J Gastroenterol 30, 398–402 (1995). https://doi.org/10.1007/BF02347518

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02347518

Key words

Navigation