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Lipid composition and fatty acid analysis ofHelicobacter pylori

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Abstract

Lipids extracted fromHelicobacter pylori were separated into lipid classes by thin-layer chromatography. SimpleH. pylori lipids consisted of cholesterol esters, triglycerides, free fatty acids, cholesterol, diacylglycerols, and monoacylglycerols. Fatty acids were released from each lipid class by acid methanolysis, and analyzed by gas liquid chromatography and mass spectrometry. Unique methoxy fatty acids, including 11-methoxy heptadecanoic and 11-methoxy nonadecanoic acids, were the major components of the cholesterol esters and triglycerides. The predominance of methoxy fatty acids in the cholesterol esters ofH. pylori may contribute to the acid-resistant characteristic of this bacillus.

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Inamoto, Y., Hamanaka, S., Hamanaka, Y. et al. Lipid composition and fatty acid analysis ofHelicobacter pylori . J Gastroenterol 30, 315–318 (1995). https://doi.org/10.1007/BF02347505

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  • DOI: https://doi.org/10.1007/BF02347505

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