Skip to main content
Log in

Morphometric classification of the neurosecretory granules in the rat pars nervosa

  • Published:
Zeitschrift für Zellforschung und Mikroskopische Anatomie Aims and scope Submit manuscript

Summary

The distribution of the diameters of the neurosecretory granules in the rat pars nervosa (measured from electron micrographs taken at 40 000 × ) was compared among axons by nonparametric statistical methods and the axons were classified into five groups with median granule diameters of 143, 155, 167, 180 and 193 nm. We suggested that these five axon types carried different secretory substances contained in the pars nervosa.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Bern, H. A., Nishioka, R. S., Mewaldt, L. R., Farner, D. S.: Photoperiodic and osmotic influences on the ultrastructure of the hypothalamic neurosecretory system of the White-crowned sparrow,Zonotrichia leucophrys gambelii. Z. Zellforsch.69, 198–227 (1966)

    Article  CAS  PubMed  Google Scholar 

  • Bliss, C. I.: Statistics in Biology. Vol. 1, p. 125–151. New York: McGraw-Hill 1967

    Google Scholar 

  • Duncan, D.: An electron microscopic study of the neurohypophysis of a bird,Gallus domesticus. Anat. Rec.125, 457–472 (1956)

    Article  CAS  PubMed  Google Scholar 

  • Fujita, H., Hartmann, J. F.: Electron microscopy of neurohypophysis in normal, adrenaline-treated and pilocarpine-treated rabbits. Z. Zellforsch. 54, 734–763 (1961)

    Article  CAS  PubMed  Google Scholar 

  • Gerschenfeld, H. M., Tramezzani, J. H., de Robertis, E.: Ultrastructure and function in neurohypophysis of the toad. Endocrinology66, 741–762 (1960)

    CAS  PubMed  Google Scholar 

  • Ishii, S.: Classification and identification of neurosecretory granules in the median eminence. In: Brain-Endocrine Interaction, Median Eminence: Structure and Function. Eds. Knigge, K. M., Scott, D. E., Weindl, A., p. 119–141. Basel: S. Karger 1972

    Google Scholar 

  • Ishii, S., Hashimoto, K.: Classification of neurosecretory granules of the equine pars nervosa by means of statistical methods. Zoological Magazine83, in press (1974)

  • Kobayashi, H., Bern, H. A., Nishioka, R. S., Hyodo, Y.: The hypothalamo-hypophyseal neurosecretory system of the parakeetMelopsittacus undulatus. Gen. comp. Endocr.1, 545–564 (1961)

    Article  CAS  PubMed  Google Scholar 

  • Kobayashi, H., Hirano, T., Oota, Y.: Electron microscopic and pharmacological studies on the median eminence and pars nervosa. Archives d'Anatomie microscopique54, 277–294 (1965)

    CAS  Google Scholar 

  • Kobayashi, H., Matsui, T., Ishii, S.: Functional electron microscopy of the hypothalamic median eminence. Internat. Rev. Cytol.29, 281–381 (1970)

    CAS  Google Scholar 

  • Kobayashi, H., Oota, Y.: Functional electron microscopy of the vertebrate neurosecretory storage-release organs. Gunma Symp. Endocrinol.1, 63–79 (1964)

    Google Scholar 

  • Kurosumi, K., Matsuzawa, T., Shibasaki, S.: Electron microscopic studies on the pars nervosa and intermedia and their morphological interrelation in the normal rat hypophysis. Gen. comp. Endocrinol.1, 433–452 (1961)

    Article  CAS  PubMed  Google Scholar 

  • Matsui, T.: Fine structure of the posterior median eminence of the pigeon,Columba livia domestica. Jour. Fac. Sci. Univ. Tokyo, IV11, 49–70 (1966)

    Google Scholar 

  • Monroe, B. G.: A comparative study of the ultrastructure of the median eminence, infundibular stem and neural lobe of the hypophysis of the rat. Z. Zellforsch.76, 405–432 (1967)

    Article  CAS  PubMed  Google Scholar 

  • Oksche, A.: Eine licht- und elektronenmikroskopische Analyse des neuroendokrinen Zwischenhirn-Vorderlappen-Komplexes der Vögel. In: Neurosecretion (F. Stutinsky, ed.), p. 77–88. Berlin: Springer-Verlag 1967

    Google Scholar 

  • Oota, Y., Kawabata, I., Kurosumi, K.: Electron microscope studies on the rat hypothalamohypophyseal neurosecretory system. Jap. Jour. Exp. Morph.20, 65–83 (1966)

    Google Scholar 

  • Palay, S. L.: An electron microscope study of the neurohypophysis in normal, hydrated, and dehydrated rats. Anat. Rec.121, 348 (1955)

    Google Scholar 

  • Rodriguez, E. M.: The comparative morphology of neural lobes of species with different neurohypophysial hormones. Mem. Soc. Endocrinol.19, 263–292 (1971)

    Google Scholar 

  • Siegel, S.: Nonparametric Statistics for the Behavioral Sciences. New York: McGraw-Hill

  • Zambrano, D., de Robertis, E.: Ultrastructure of the peptidergic and monoaminergic neurons in the hypothalamic neurosecretory system of anuran batracians. Z. Zellforsch.90, 230–244 (1968)

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

This investigation is supported by a grant from the Population Council, New York and grant from the Ministry of Education. Authors are grateful to Japan Electron Optics Laboratory Company for their technical assistance with the electron microscopy and to Miss Kazue Yamamoto for her help in preparing the figures.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ishii, S., Thomas, P. Morphometric classification of the neurosecretory granules in the rat pars nervosa. Z.Zellforsch 146, 463–471 (1973). https://doi.org/10.1007/BF02347176

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02347176

Key words

Navigation