Summary
1. Measul'ement of cutaneous capillary resistance in fifty eight diabetics aged less than fifty-one years showed a significant lowering of this resistance when compared with a control group of one hundred and seven normals. — 2. In a group of thirty-five diabetics of fifteen years duration twenty-two showed reduced capillary resistance and this was associated with a high incidence of retinal haemorrhages. In the remaining thirteen, capillary resistance was not reduced and retinal haemorrhage was minimal. — 3. A further group of ten diabetics with deteriorating retinopathy had a very low cutaneous capillary resistance. Ten diabetics with no retinopathy at all after fifteen years had high capillary resistance.
Résumé
1. La mesure de la résistance capillaire cutanée chez cinquante-huit diabétiques âgés de moins de cinquante et un ans a montré un ahaissement significatif de cette résistance par rapport à un groupe témoin de centsept sujets normaux. — 2. Dans un groupe de trente-cinq diabétiques depuis quinze arts, vingt-deux ont montré une résistance capillaire réduite et cecei était associé à une grande fréquence d'hémorragies rétiniennes. Chez les treize autres, la résistance capillaire n'était pas réduite et l'hémorragie rétinienne était minime. — 3. Un autre groupe de dix diabétiques avec rétinopathie dégénégrative avait une résistance capillaire cutange très faible. Dix diabétiques sans rétinopathie du tout au bout de quinze ans avaient une résistance capillaire élevée.
Zusammenfassung
1. Die Messung der Resistenz der Hautcapillaren bei 58 Diabetikern unter 51 Jahren ergab beim Vergleich mit 10 Normalpersonen signifikant erniedrigte Werte. — 2. 22 von 35 Diabetikern mit einer Erkrankungsdauer von 15 Jahren wiesen eine herabgesetzte Capillarresistenz auf und gleichzeitig eine hohe Frequenz von Retinablutungen. Bei den restlichen 13 war die Capillarresistenz nicht verringert und fanden sich kaum Retinablutungen. — 3. Eine weitere Gruppe von 10 Diabetikern mit fortschreitender Retinopathie wiesen eine sehr stark herabgesetzte Capillarresistenz in den Hautgefäßen auf. Bei 10 Patienten ohne Hinweise auf eine Retinopathie nach 15 Jahren Diabetes-Dauer fand sich eine hohe Capillarresistenz.
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Supported by a generous grant from the Prevention of Blindness Committee of the Royal National Institute for the Blind and by Zyma (U.K.) Ltd.
Supported by a Pfizer Research Fellowship.
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Hunter, P.R., Bloom, A., Kelsey, J.H. et al. Cutaneous capillary resistance and retinal haemorrhage in diabetes. Diabetologia 7, 20–24 (1971). https://doi.org/10.1007/BF02346249
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DOI: https://doi.org/10.1007/BF02346249