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Fine structure and innervation of the avian adrenal gland

IV. Fine structure of interrenal cells

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Summary

Cords of interrenal-cells of birds resemble “tubes without lumina”, which are lined by columnar cells arranged in double rows. A subcapsular and an inner zone of the interrenal gland may be distinguished according to the structure of their mitochondria, the existence of smooth and rough surfaced endoplasmic reticulum, and the lipid contents. The cells of the inner zone are clearly polarized. The extrusion of lipid by exocytosis is discussed. It is often difficult to decide, whether ultrastructural details are species - specific or indicate a certain state of function.

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References

  • Arvy, L.: Histo-enzymologie des glandes endocrines. Paris: Gauthier-Villars 1963

    Google Scholar 

  • Barnard, T.: The ultrastructural differentiation of brown adipose tissue in the rat. J. Ultrastruct. Res.29, 311–332 (1969)

    CAS  PubMed  Google Scholar 

  • Belt, W. D., Sheridan, M. N., Knouff, R. A., Hartmann, F. A.: Fine structural study of a possible mechanism of secretion by the interrenal cells of the brown pelican. Z. Zellforsch.68, 864–873 (1965)

    Article  CAS  PubMed  Google Scholar 

  • Rhattacharjee, D., Gosh, A.: Probable cellular site of glucocorticoid secretion in the pigeon — an experimental study. Endokrinologie46, 262–270 (1964)

    Google Scholar 

  • Bhattacharyya, T. K., Gosh, A.: Histological and histochemical studies of the adrenal cortex in experimentally hypothyroid pigeons. Acta anat. (Basel)52, 150–162 (1963)

    CAS  Google Scholar 

  • Birmingham, M. K., Elliot, F. H., Valère, P.H.L.: The need for the presence of calcium for the stimulation in vitro of rat adrenal glands by adrenocorticotrophic hormone. Endocrinology53, 687–689 (1953)

    CAS  PubMed  Google Scholar 

  • Black, V. H., Christensen, A. K.: Differentiation of interstitial cells and Sertoli cells in fetal guinea pig testes. Amer. J. Anat.124, 211–238 (1969)

    Article  CAS  PubMed  Google Scholar 

  • Blanchette, E. J.: Ovarian steroid cells. II. The lutein cell. J. Cell Biol.31, 517–542 (1966)

    CAS  PubMed  Google Scholar 

  • Bloodworth, J.M.B., Powers, K. L.: The ultrastructure of the normal dog adrenal. J. Anat. (Lond.)102, 457–476 (1968)

    Google Scholar 

  • Boddingius, J.: An argyrophil fibrillar system and amitotic nuclear division in pars intermedia cells of the rainbow trout (Salmo irideus). Z. Zellforsch.108, 59–80 (1970)

    Article  CAS  PubMed  Google Scholar 

  • Carr, I., Carr, J.: Membranes whorls in the testicular interstitial cell. Anat. Rec.144, 143–147 (1962)

    Article  CAS  PubMed  Google Scholar 

  • Chester Jones, I.: The adrenal cortex. Cambridge University Press 1957

  • Christensen, A. K.: The fine structure of testicular interstitial cells in guinea pigs. J. Cell Biol.26, 911–935 (1965)

    Article  Google Scholar 

  • Christensen, A. K., Fawcett, D. W.: The fine structure of testicular interstitial cells in mice. Amer. J. Anat.118, 551–572 (1966)

    Article  CAS  PubMed  Google Scholar 

  • Dahl, E.: Studies on the fine structure of ovarian interstitial tissue. 4. Effects of steroids on the thecal gland of the domestic fowl. Z. Zellforsch.113, 111–132 (1971a)

    CAS  PubMed  Google Scholar 

  • Dahl, E.: Studies on the fine structure of ovarian interstitial tissue. 5. Effects of gonadotropins on the thecal gland of the domestic fowl. Z. Zellforsch.113, 133–156 (1971b)

    CAS  PubMed  Google Scholar 

  • Deane, H. W.: The adrenocortical hormones. In: Handbuch der experimentellen Pharmakologie, Bd XIV/1. Berlin-Göttingen-Heidelberg: Springer 1972

    Google Scholar 

  • De Roos, R.: The corticoids of the avian adrenal gland. Gen. comp. Endocrinol.1, 494–512 (1961)

    Article  Google Scholar 

  • De Roos, R., De Roos, C.: Effects of mammalian corticotropin and chicken adenohypophyseal extracts on steroideogenesis by chicken adrenal tissue in vitro. Gen. comp. Endocr.4, 602–607 (1964)

    Google Scholar 

  • Donaldson, E. M., Holmes, W. N.: Corticosteroidogenesis in fresh water and saline maintained duck (Anas platyrhynchos). J. Endocr.32, 329–336 (1965)

    CAS  PubMed  Google Scholar 

  • Fawcett, D. W., Burgos, M. H.: Studies on the fine structure of the mammalian testis. II. The human interstitial tissue. Amer. J. Anat.107, 245–269 (1960)

    Article  Google Scholar 

  • Fawcett, D. W., Long, J. A., Jones, A. L.: The ultrastructure of endocrine glands. Recent Progr. Hormone Res.25, 315–380 (1969)

    CAS  PubMed  Google Scholar 

  • Fujita, H.: An electron microscopic study of the adrenal cortical tissue of the domestic fowl. Z. Zellforsch.55, 80–88 (1961)

    Article  CAS  PubMed  Google Scholar 

  • Fujita, H., Machino, M., Tokura, T.: Some observations on the fine structure of the adrenal cortical cells of domestic fowl. Arch. histol. jap.24, 77–89 (1963)

    CAS  PubMed  Google Scholar 

  • Gorgas, K.: Über die Ultrastruktur der Zona reticularis der Nebennierenrinde vom Nutria (Myocastor coypus Molina) unter besonderer Berücksichtigung der sog. dunklen Zellen. Ergebn. Anat. Entwickl.-Gesch. 45/5. Berlin-Heidelberg-New York: Springer 1971

    Google Scholar 

  • Gosh, A.: A comparative study of the histochemistry of the avian adrenals. Gen. comp. Endocr. Suppl.1, 75–80 (1962)

    Google Scholar 

  • Grignon, G., Hatier, R., Guedenet, J. C., Dollander, A.: Aspects ultrastructuraux de la glande surrénale au tours du développement chez l'embryon de Poulet. C.R. Soc. Biol. (Paris)160, 1654–1657 (1966)

    CAS  Google Scholar 

  • Harrison, G. A.: Some observations on the presence of annulate lamellae in alligator and sea gull adrenal cortical cells. J. Ultrastruct. Res.14, 158–166 (1966)

    Article  Google Scholar 

  • Hartmann, F. A., Brownell, K. A.: The Adrenal Gland. Philadelphia: Lea and Febiger 1949

    Google Scholar 

  • Idelman, S.: Contribution à la cytophysiologie infrastructurale de la corticosurrénale chez le Rat albinos. Ann. Sci. nat. Zool.8, 205–362 (1966)

    Google Scholar 

  • Kjaerheim, A.: Studies on adrenocortical ultrastructure. The interrenal cell of the domestic fowl as seen after glutaraldehyde perfusion fixation. Z. Zellforsch.91, 429–455 (1968a)

    CAS  PubMed  Google Scholar 

  • Kjaerheim, A.: Studies of adrenocortical ultrastructure. 3. Effects of dexamethasone and medroxyprogesterone on interrenal cells of the domestic fowl. Z. Zellforsch.91, 456–474 (1968b)

    CAS  PubMed  Google Scholar 

  • Kjaerheim, A.: Studies on adrenocortical ultrastructure. 4. Effects of ACTH on interrenal cells of the domestic fowl. J. Microscopie7, 715–738 (1968c)

    Google Scholar 

  • Kjaerheim, A., Kondics, L.: Ultrastructure of the interrenal cells in the hen. J. Ultrastruct. Res.14, 419 (1966)

    Google Scholar 

  • Kondics, L.: Die Wirkung von ACTH und Prednisolon auf die funktionale Zonation der Nebenniere bei der Taube (Columba domestica). Acta morph. Acad. Sci. hung.13, 233–240 (1964)

    Google Scholar 

  • Kondics, L., Kjaerheim, A.: The zonation of interrenal cells in fowls (an electron microscopic study). Z. Zellforsch.70, 81–90 (1966)

    Article  Google Scholar 

  • Kühnel, W.: Struktur und Cytochemie der Harderschen Drüse vom Kaninchen. Z. Zellforsch.119, 384–404 (1971)

    Article  PubMed  Google Scholar 

  • Latimer, H. B., Landwer, M. F.: The relative volumes and the arrangement of the cortical and the medullary cells of the suprarenal gland of the chicken. Amer. Ass. Anat., Anat. Rec.29, 389 (1925)

    Google Scholar 

  • Lindner, E.: Die Sacculi mitochondriales der Diskochondrien und Sphaerochondrien in der Nebennierenrinde vom Igel (Erinaceus europaeus L.). Z. Zellforsch.72, 212–235 (1966)

    Article  CAS  PubMed  Google Scholar 

  • Long, J. A., Jones, A. L.: The fine structure of the zona glomerulosa and the zona fasciculata of the adrenal cortex of the opossum. Amer. J. Anat.120, 463–488 (1967)

    Article  CAS  PubMed  Google Scholar 

  • Long, J. A., Jones, A. L.: Alterations in fine structure of the opossum adrenal cortex following sodium deprivation. Anat. Rec.166, 1–26 (1970)

    Article  CAS  PubMed  Google Scholar 

  • Luse, S. A.: Fine structure of adrenal cortex. In: The adrenal cortex, p. 1–59. Boston: Little, Brown and Co. 1967

    Google Scholar 

  • Merkow, L.-P., Acevedo, H. F., Slifkin, M., Caito, B. J.: Studies on the interstitial cells of the testis. I. The ultrastructure in the immature guinea pig and the effect of stimulation with human chorionic gonadotropin. Amer. J. Path.53, 47–61 (1968a)

    CAS  PubMed  Google Scholar 

  • Merkow, L.-P., Pardo, M.: Studies on the interstitial cells of the testis. II. The ultrastructure in the adult guinea pig and the effect of stimulation with human chorionic gonadotropin. Amer. J. Path.53, 989–1007 (1968b)

    CAS  PubMed  Google Scholar 

  • Merkow, L.-P., Slifkin, M., Acevedo, H. F., Pardo, M.: Ultrastructural, in vitro, and virological studies on a hilar cell tumor of the ovary. 7th Intern. Congr. Electron Microsc. Grenoble3, 921–922 (1970)

    Google Scholar 

  • Miller, R. A., Riddle, O.: Stimulation of adrenal cortex of pigeons by anterior pituitary hormones and by their secondary products. Proc. Soc. exp. Biol. (N. Y.)41, 518–522 (1939)

    CAS  Google Scholar 

  • Miller, R. A., Riddle, O.: The cytology of the adrenal cortex of normal pigeons and in experimentally induced atrophy and hypertrophy. Amer. J. Anat.71, 311–341 (1942)

    Article  CAS  Google Scholar 

  • Moens, L., Coessens, R.: Seasonal variations in the adrenal cortex cells of the house sparrow,Passer domesticus (L.), with special reference to a possible zonation. Gen. comp. Endocr.15, 95–100 (1970)

    Article  CAS  PubMed  Google Scholar 

  • Moses, H. L., Davies, W. W., Rosenthal, A. S., Garren, L. D.: Adrenal cholesterol: localization by electron microscope autoradiography. Science163, 1203–1205 (1969)

    CAS  PubMed  Google Scholar 

  • Murakami, M.: Elektronenmikroskopische Untersuchungen am interstitiellen Gewebe des Rattenhodens, unter besonderer Berücksichtigung der Leydigschen Zwischenzellen. Z. Zellforsch.72, 139–156 (1966)

    Article  CAS  PubMed  Google Scholar 

  • Murakami, M., Gonara, S., Yoshida, T., Shigematsu, S.: Elektronenmikroskopische Beobachtungen bei einem Leydigzelltumor eines Erwachsenen. Endokrinologie52, 335–351 (1968)

    PubMed  Google Scholar 

  • Nickerson, P. A., Skelton, F. R., Molteni, A.: Observation of filaments in the adrenal of androgen-treated rats. J. Cell Biol.47, 277–280 (1970)

    Article  CAS  PubMed  Google Scholar 

  • Nussdorfer, G. G.: The possible functional role of lysosomes in the cells of the rat adrenal cortex (Zona fasciculata). Lo Sperim.119, 55–71 (1969)

    CAS  Google Scholar 

  • Palade, G. E., Schidlowsky, G.: Functional association of mitochondria and lipid inclusions. Anat. Rec.130, 352–353 (1958)

    Google Scholar 

  • Parks, H. F.: An experimental study of microscopic and submicroscopic lipid inclusions in hepatic cells of the mouse. Amer. J. Anat.120, 253–280 (1967)

    Article  Google Scholar 

  • Péczely, P.: The adaption to saltwater conditions of the adrenal structure in various bird species. Acta biol. Acad. Sci. hung.15, 171–179 (1964)

    PubMed  Google Scholar 

  • Péczely, P.: Effect of thirst and water load on the hypothalamic regulation of the adrenal in the pigeon (Columba livia domestics L.). Acts morph. Acad. Sci. hung.14, 227–244 (1966)

    Google Scholar 

  • Pehlemann, F. W.: Die amitotische Zellteilung. Eine elektronenmikroskopische Untersuchung an Interrenalzellen vonRana temporaria L. Z. Zellforsch.84, 516–548 (1968)

    CAS  PubMed  Google Scholar 

  • Pehlemann, F. W., Hanke, W.: Funktionsmorphologie des Interrenalorgans vonRana temporaria L. Z. Zellforsch.89, 281–302 (1968)

    Article  CAS  PubMed  Google Scholar 

  • Rabl., H.: Die Entwicklung und Struktur der Nebenniere bei den Vögeln. Arch. mikr. Anat.38, 492–523 (1891)

    Google Scholar 

  • Rhodin, J.A.G.: The ultrastructure of the adrenal cortex of the rat under normal and experimental conditions. J. Ultrastruct. Res.34, 23–71 (1971)

    Article  CAS  PubMed  Google Scholar 

  • Rubin, R. P., Jaanus, S. D., Miele, E.: Calcium dependent corticosteroid release from the perfused cat adrenal gland. Experientia (Basel)25, 1327–1328 (1969)

    CAS  Google Scholar 

  • Schmidt, W.: Submikroskopische Befunde an den Zwischenzellen des Katzenovariums nach Oestrogenvorbehandlung und folgender Gonadotropinstimulierung. Z. mikr.-anat. Forsch.81, 185–208 (1969)

    CAS  PubMed  Google Scholar 

  • Shelton, J., Jones, A. L.: Ultrastructural changes in mouse adrenal cortex associated with low and high sodium diets. Anat. Rec.163. 262 (1969)

    Google Scholar 

  • Sheridan, M. A., Hartman, F. A.: The fine structure of the interrenal cells of the brown pelican. Acta anat. (Basel)53, 55–65 (1963)

    CAS  Google Scholar 

  • Smith, A. D.: Summing up: some implications of the neuron as a secreting cell. Phil. Trans. B,261, 423–437 (1971)

    CAS  Google Scholar 

  • Szabó, D., Stark, E., Varga, B.: Electron-microscopic study of the functional changes and the acid phosphatase reaction on the fasciculate zone of the rat adrenal. Acta morph. Acad. Sci. hung.14, 342 (1966)

    Google Scholar 

  • Unsicker, K.: Über den Feinbau der Hiluszwischenzellen im Ovar des Schweins (Sus scrota L.). Mit Bemerkungen zur Frage der Innervation. Z. Zellforsch.109, 495–516 (1970)

    CAS  PubMed  Google Scholar 

  • Unsicker, K.: Über den Feinbau von Marksträngen und Markschläuchen im Ovar juveniler und geschlechtsreifer Schweine (Sus scrota L.). Z. Zellforsch.114, 334–364 (1971)

    Article  Google Scholar 

  • Unsicker, K.: Fine structure and innervation of the avian adrenal gland. I. Fine structure of adrenal chromaffin cells and ganglion cells. Z. Zellforsch. (in press) (1973a)

  • Unsicker, K.: Fine structure and innervation of the avian adrenal gland. II. Cholinergic innervation of adrenal chromaffin cells. Z. Zellforsch. (in press) (1973b)

  • Unsicker, K.: Fine structure and innervation of the avian adrenal gland. III. Non-cholinergic nerve fibres. Z. Zellforsch. (in press) (1973c)

  • Unsicker, K.: Fine structure and innervation of the avian adrenal gland. Innervation of interrenal cells. Z. Zellforsch. (in press) (1973e)

  • Vincent, S.: The comparative histology of the suprarenal capsules. Intern. Mschr. Anat. Physiol.15, 282–326 (1898a)

    Google Scholar 

  • Vincent, S.: Further observations upon the comparative physiology of the suprarenal capsules. Proc. roy. Soc.62, 176–178 (1898b)

    Google Scholar 

  • Volk, T. L.: Ultrastructure of the cortical cell of the interrenal gland of the american bullfrog (Rana catesbeiana). Z. Zellforsch.123, 470–485 (1972)

    Article  CAS  PubMed  Google Scholar 

  • Whitehouse, B. J., Vinson, G. P.: Pathways of corticosteroid biosynthesis in duck adrenal glands. Gen. comp. Endocr.9, 161–171 (1967)

    Article  CAS  PubMed  Google Scholar 

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This work was supported by a grant from the “Deutsche Forschungsgemeinschaft” (Un 34/1).

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Unsicker, K. Fine structure and innervation of the avian adrenal gland. Z.Zellforsch 146, 385–402 (1973). https://doi.org/10.1007/BF02346230

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