Summary
The arcuate nucleus of untreated (control) and castrated adult mice was studied with the electron microscope. Nucleolus-like bodies (NLB) were found in the cytoplasm and occasionally in the dendrites of arcuate neurons. NLB were spherical or ovoid, 0.7–1.5µm in diameter; they were composed of granules 100–150 Å and 200 Å in diameter, and filaments ∼70 Å in diameter. NLB were frequently associated with free ribosomes and cisternae of the rough endoplasmic reticulum. Light microscopic studies with basic dyes and enzymatic digestions showed that these bodies contained some RNA. There was no significant change in the number of NLB in castrated animals.
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This investigation was supported by a fellowship of the Alexander von Humboldt-Stiftung to the author. The author is grateful to Professor A. Oksche, Giessen, and to Professor J. Sloper, London, for their interest and criticism.
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Santolaya, R.C. Nucleolus-like bodies in the neuronal cytoplasm of the mouse arcuate nucleus. Z.Zellforsch 146, 319–328 (1973). https://doi.org/10.1007/BF02346224
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DOI: https://doi.org/10.1007/BF02346224