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Nickel and chromium release from stents into isotonic NaCl solution investigated with the aid of neutron activation analysis

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Abstract

Stent placement has become an effective treatment for abrupt or threatened vessel closure in recent years. As a preliminary investigation on the allergy problem towards to Ni and Cr metals from implanted stent, the release of the two elements from stents into isotonic NaCl solution was investigated. Trace amounts of Ni and Cr metals released from stents are successfully determined by neutron activation analysis (NAA). An extreme experimental condition is applied in the NAA procedure to reach a low detection limit of 1 ng Ni. A conclusion is given about the influence on the Ni and Cr release from gold coating, from the expansion, and from the different incubation periods.

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Authors and Affiliations

  1. Institut für Radiochemie der Technischen Universität München, D-85747, Garching, Germany

    X. Lin, G. Portenlaenger & R. Henkelmann

  2. Klinikum rechts der Isar der Technischen Universität München, D-81675, Munich, Germany

    Ch. Schulz & E. Alt

Authors
  1. X. Lin
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  2. G. Portenlaenger
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  3. R. Henkelmann
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  4. Ch. Schulz
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  5. E. Alt
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Lin, X., Portenlaenger, G., Henkelmann, R. et al. Nickel and chromium release from stents into isotonic NaCl solution investigated with the aid of neutron activation analysis. J Radioanal Nucl Chem 242, 565–568 (1999). https://doi.org/10.1007/BF02345595

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  • DOI: https://doi.org/10.1007/BF02345595

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