Skip to main content
SpringerLink
Log in

Separation of carrier-free111In formed in the12C+Rh reaction

  • Short Communication
  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

An alternative reaction route for the production of111In from rhodium target bombarded with a12C beam has been developed. Sulfate fusion was adapted for dissolution of the irradiated rhodium metal target. Indium was coprecipitated with La(OH)3 and purified by solvent extraction of the InBr3 complex into di-isopropyl ether and back extraction in 6M HCl. The chemical yield of the separation, determined using105Rh as tracer, was found to be above 90%. The radionuclidic purity of the separated111In satisfies the requirement prescribed for radiopharmaceutical preparations. The radioactivity yield achieved using this route was about 0.2 MBq/μAh.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. R. L. Hayes, K. F. Hubner, Metal ions in Biological Systems, Vol. 16H. Sigel (Ed.), Chapter 17: Basis for the clinical use of gallium and indium radionuclides. Marcel Dekker Inc., New York and Basel, 1983.

    Google Scholar 

  2. D. J. Hnatowich, J. McGann, Nucl. Med. Biol., 14 (1987) 563.

    CAS  Google Scholar 

  3. S. C. Srivastava, L. F. Mauser, K. L. Kolsky, Criteria for the selection and production of radionuclides for diagnosis and therapy. 208th American Chemical Society Meeting, Washington, Paper NUCL 29, 1994, p. 1072.

  4. K. Yoshihara, H. Kaji, T. Mitsugashira, S. Suzuki, Radiochem. Radioanal. Letters., 58 (1983) 9.

    CAS  Google Scholar 

  5. Y. Nakamura, H. Nakahara, Y. Murakami, Radioisotopes, 28 (1979) 675.

    CAS  Google Scholar 

  6. A. Malinim, N. Kurenkov, M. Kozlova, A. Sevastyanova, Radiochem. Radioanal. Letters, 59 (1983) 213.

    Google Scholar 

  7. S. Chattopadhyay, M. K. Das, B. R. Sarkar, N. Ramamoorthy, Appl. Radiation Isotopes, 48 (1997) 1003.

    Google Scholar 

  8. S. K. Das, R. Guin, S. K. Saha, Appl. Radiation Isotopes, 47 (1996) 293.

    CAS  Google Scholar 

  9. D. Zhou, Studies on extraction technology method of medical nuclide111In. China Nuclear Information Centre, CNIC-00961; Suinsi-0011 Report, 1995, p. 12.

  10. D. N. Sunderman, C. W. Townley, The Radiochemistry of Indium, National Academy of Sciences, National Research Council. Nuclear Science Series, 1960.

Download references

Author information

Authors and Affiliations

  1. Isotope Division, Bhabha Atomic Research Centre, 400 085, Mumbai, India

    S. V. Thakare

  2. Radiochemistry Division, Bhabha Atomic Research Centre, 400 085, Mumbai, India

    A. G. C. Nair, S. Chakrabarty & B. S. Tomar

Authors
  1. S. V. Thakare
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. G. C. Nair
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. Chakrabarty
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. B. S. Tomar
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Thakare, S.V., Nair, A.G.C., Chakrabarty, S. et al. Separation of carrier-free111In formed in the12C+Rh reaction. J Radioanal Nucl Chem 242, 537–539 (1999). https://doi.org/10.1007/BF02345589

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02345589

Keywords

Search

Navigation