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Haemorheology in patients with branch retinal vein occlusion with and without risk factors

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Abstract

• Purpose: The study was carried out to ascertain the role of blood viscosity in patients with branch retinal vein occlusion (BR-VO) with and without risk factors. • Methods: In 292 patients with acute BRVO (mean age 65 ± 10 years) and 292 controls matched for gender, age, and cardiovascular risk factors, haematocrit, plasma viscosity, erythrocyte aggregation and erythrocyte rigidity were measured. A subgroup analysis in patients with and without risk factors was performed. • Results: Haematocrit and plasma viscosity values were significantly higher in BRVO patients than in controls, but erythrocyte rigidity and erythrocyte aggregaton did not differ. Subgroup analysis revealed no differences in haematocrit and plasma viscosity values between patients with and those without cardioavascular risk factors. • Conclusions: This study shows increased plasma viscosity and haematocrit values in patients with BRVO which are not associated with the presence of other cardiovascular risk factors. Thus, changes in blood fluidity appear to be important factors in the pathogenesis of BRVO.

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Authors and Affiliations

  1. Augenklinik der Medizinischen Fakultät der RWTH Aachen, Pauwelstrasse 30, D-52057, Aachen, Germany

    Andreas Remky, Oliver Arend, Martin Reim & Sebastian Wolf

  2. Schepens Eye Research Institute, 20 Staniford Street, 02114, Boston, MA, USA

    Andreas Remky

  3. Abteilung für klinische Hämostaseologie und Transfusionsmedizin, Universität des Saarlandes, D-66421, Homburg, Germany

    Friedrich Jung & Holger Kiesewetter

  4. Institut für Transfusionsmedizin und Immunhämatologie, Universitätskliniken Charité, Humboldt Universität, D-10098, Berlin, Germany

    Holger Kiesewetter

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  1. Andreas Remky
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  2. Oliver Arend
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  3. Friedrich Jung
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  4. Holger Kiesewetter
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  6. Sebastian Wolf
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Remky, A., Arend, O., Jung, F. et al. Haemorheology in patients with branch retinal vein occlusion with and without risk factors. Graefe's Arch Clin Exp Ophthalmol 234 (Suppl 1), S8–S12 (1996). https://doi.org/10.1007/BF02343041

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  • DOI: https://doi.org/10.1007/BF02343041

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