Summary
A considerable fatigue attained by prolonged swimming caused a marked reduction of the intensity of nucleic acid renewal in the regenerating rat liver 24 hours after partial hepatectomy (RNA by 28%, DNA by 48%) without affecting the content of these acids in the organ investigated.
A model is suggested for studying the efficancy of low doses of ionizing radiation, i.e., reduction of nucleic acid synthesis in the regenerating liver of partially hepatectomized rats, resulting from prolonged fatigue.
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Literature Cited
L. G. Leshkevich, Fiziol. zh. SSSR, 4, 475 (1951).
N. R. Chagobets, Ukr. biokhim. zh., 2, 204 (1959).
N. N. Yakovlev and L. I. Yampol'skaya, Byull. éksper. biol.,24,10, 287 (1947).
N. N. Yakovlev, Fiziol. zh. SSSR, 6, 717 (1948).
N. N. Yakovlev, Fiziol. zh. SSSR, 6, 744 (1950).
N. N. Yakovlev, Ukr. biokhim. zh., 1, 113 (1952).
L. I. Yampol'skaya and N. N. Yakovlev, Fiziol. zh. SSSR, 1, 110 (1951).
H. Schurnann, Z. ges. exp. Med. (1939),106, p. 59.
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Rakhmanova, T.B. Effect of fatigue on nucleic acid metabolism in the regenerating liver of partially hepatectomized rats. Bull Exp Biol Med 56, 1247–1248 (1963). https://doi.org/10.1007/BF02342830
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DOI: https://doi.org/10.1007/BF02342830