Summary
Experiments were carried out on 6 dogs with a Pavlov pouch and gastric fistula. Studies were made of gastric secretion, motility and evacuation in normal conditions and when hyper- or hypothyroldism had been induced in the animals for a period of 1 year. Thyroid function was altered by thyroidin or methylthiourasil given by mouth. It was found that the gastric functions studied were influenced in two opposite ways. The pathological changes occurring in hypothyroidism created unfavorable conditions for digestion, and this might lead to diarrhea and loss of weight. In hypothyroidism conditions were favorable, and the animals gained weight; however, decreased gastric motility might lead to constipation.
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Sholokhov, S.V. A functional connection between the thyroid gland and the stomach. Bull Exp Biol Med 56, 1195–1199 (1963). https://doi.org/10.1007/BF02342817
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DOI: https://doi.org/10.1007/BF02342817