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The effect of electrical polarization of the motor nerve endings on the transmission through them of single impulses

  • Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

A frog nerve-muscle preparation was used to study the effects of depolarization and hyperpolarization of the transmission of single impulses at nerve endings. The efficacy of synaptic transmission was determined by the value of the end-plate potential led off intracellularly from the muscle fiber.

Depolarization of the nerve endings produced a rapid reduction of up to 10–20% in the trans-synaptic action of the ending. Hyperpolarization of the endings caused the efficacy of trans-synaptic action to increase slowly for three minutes. In such cases the end-plate potential rose to 3 or 4 times the control level. These changes were observed only with a local polarization of the region of the nerve endings, and were absent when the preterminal branches of the nerve were polarized.

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Literature Cited

  1. E. de Robertis and H. S. Bennet, Fed. Proc. (1954),13, p. 35.

    Google Scholar 

  2. F. de Robertis and C. Franchi, J. biophys. biochem. Cytol. (1956),2, p. 307.

    Google Scholar 

  3. J. del Castillo and B. Katz, J. Physiol., London (1954),124, p. 586.

    Google Scholar 

  4. J. C. Eccles, P. G. Kostyuk, and R. F. Shmidt, ibid. (1962),162, p. 138.

    CAS  Google Scholar 

  5. S. Hagiwara and I. Tasaki, J. Physiol. (1958),143, p. 114.

    CAS  PubMed  Google Scholar 

  6. J. I. Hubbard and W. D. Willis, Nature (1962),193, p. 174.

    CAS  PubMed  Google Scholar 

  7. J. I. Hubbard and W. D. Willis, Nature (1962), p. 1294.

  8. J. I. Hubbard, and W. D. Willis, J. Physiol. London (1962),163, p. 115.

    CAS  PubMed  Google Scholar 

  9. A. W. Liley, ibid (1956),134, p. 427.

    CAS  PubMed  Google Scholar 

  10. A. Takeuchi and N. Takeuchi, J. gen. Physiol. (1962),45, p. 1181.

    Article  CAS  PubMed  Google Scholar 

  11. V. P. Whittaker, Biochem. J. (1959),72, p. 694.

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Laboratory of General Physiology, A. A. Bogomolets Institute of Physicology, AN Ukrainian SSR, Kiev

    I. A. Vladimirova

Authors
  1. I. A. Vladimirova
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Vladimirova, I.A. The effect of electrical polarization of the motor nerve endings on the transmission through them of single impulses. Bull Exp Biol Med 56, 1180–1183 (1963). https://doi.org/10.1007/BF02342813

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  • DOI: https://doi.org/10.1007/BF02342813

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