Summary
Twenty patients with various forms of lymphedema were studied by indirect lymphography. Isovist (Schering AG, Berlin) used for intradermal infusion is a new non-ionic, water-soluble, dimeric contrast media. Simultaneous indirect lymphography (SIL) was recommended. Characteristic patterns of lymphatics were demonstrated. The newly developed Isovist allows visualization of initial lymphatics by intradermal infusion. However, they are not opacified with direct lymphography unless valvular insufficiency is present. No systemic side effects were observed. There was only a feeling of discomfort at the injection site. The results show that indirect lymphography with the intradermal infusion of Isovist is useful for demonstrating dermal lymph vessels and facilitates the diagnosis of lymphedema.
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Gan, J.L., Chang, T.S., Fu, K.D. et al. Indirect lymphography with Isovist-300 in various forms of lymphedema. Eur J Plast Surg 14, 109–112 (1991). https://doi.org/10.1007/BF02341732
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DOI: https://doi.org/10.1007/BF02341732