Summary
A brief review of the literature in relation to time disorder and LSD-25 is given. Twenty nine patients were studied as regards their time experiences under LSD-25. Eight patients reported an altered time experience following the initial administration of the drug. Twelve patients who had not developed a time disturbance in their initial administration, received LSD-25 a second time at increased dosage, 5 of these patients then experienced a time disturbance.
There was a tendency for time disorder to be associated with visual perceptual changes and for it to occur in the non-schizophrenics. Time disorder was considered to be a non-specific response. Recent views on the nature and genesis of time disorders are discussed.
Similar content being viewed by others
References
Anastasopoulos, G., andH. Photiades: Effect of LSD-25 on relatives of schizophrenic patients. J. ment. Sci.108, 95–98 (1962).
Anderson, E. W., andK. Rawnsley: Clinical studies of lysergic acid diethyamide. Mschr. Psychiat. Neurol.128, 35–55 (1954).
Aronson, H., andA. S. Silverstein: The influence of LSD-25 on subjective time. Arch. gen. Psychiat.1, 469–472 (1959).
Becker, A. M.: Zur Psychopathologie der Lysergsäurediäthylamidwirkung. Wien. A. Nervenheilk.2, 402–440 (1949).
Bennett, C. C.: In:L. Uhr, andJ. G. Miller (eds.), Drugs and behaviour, chapt. 50. New York: Wiley 1960.
Beringer, K.: Der Meskalinrausch. Seine Geschichte und Erscheinungsweise. Berlin: Springer 1927.
Deshon, H. J., M. Rinkel, andH. C. Solomon: Mental changes experimentally produced by LSD-25. Psychiat. Quart.26, 33–54 (1952).
Finney, D. J.: The Fisher-Yates test of significance in 2 × 2 contingency tables. Biometrika35, 145–156 (1948).
Fischer, R., E. Griffin andL. Liss: Biological aspects of time in relation to (model) psychoses. Ann. N.Y. Acad. Sci.96 (Art. 1), 44–65 (1962).
Greiner, R. T., N. R. Burch andR. Edelberg: Psychopathology and psychophysiology of minimal LSD-25 dosage. Arch. Psychiat. Neurol.79, 208–210 (1958).
Guttmann, E., andW. S. Maclay: Mescalin and depersonalization. J. Neurol. Psychopath.16, 193–212 (1936).
Hoagland, H.: Problems of consciousness. Trans. 1st. Conf., p. 164–200,H. A. Abramson (ed.). New York: Josiah Macy Jr. 1950.
Hoch, P., J. P. Cattell, andH. H. Pennes: Effects of mescaline and lysergic acid (d. LSD-25). Amer. J. Psychiat.108, 579–584 (1952).
Horita, A., andJ. M. Dille: Pyretogenic effect of lysergic acid diethylamide. Science120, 1100–1101 (1954).
—, andJ. H. Gogerty: The pyretogenic effect of 5 hydroxytryptophan and its comparison with that of LSD-25. J. Pharmacol. exp. Ther.122, 195–200 (1958).
Knauer, A. W., andW. J. M. A. Maloney: A preliminary note on the psychic action of mescalin, with special reference to the mechanism of visual hallucination. J. nerv. ment. Dis.40, 425–436 (1913).
Lindeman, E., andW. Malamud: Experimental analysis of the psychopathological effects of intoxicating drugs. Amer. J. Psychiat.90, 853–881 (1934).
Mayer-Gross, W.: Experimental psychoses and other mental abnormalities produced by drugs. Brit. med. J.1951II, 317–321.
Mitchell, S. W.: The effects of anhalonium lewinii (The mescal Button). Brit. med. J.1896II, 1625–1629.
Schneider, K.: Psychopathic personalities (Trans. M. W. Hamilton), 9th edit. London: Cassell 1958.
Serko, A.: Im Mescalinrausch. Jb. Psychiat. Neurol.34, 355–366 (1913).
Sloane, B., andJ. W. Doust: Psychophysiological investigations in experimental psychoses. Results of the exhibition ofd-lysergic acid diethylamide to psychiatric patients. J. ment. Sci.100, 129–142 (1954).
Stoll, W. A.: Lysergsäure-diäthylamid ein Phantasticum aus der Mutterkorngruppe. Schweiz. Arch. Neurol. Psychiat.60, 279–323 (1947).
Weiner, H., andS. Ross: Effects ofd-amphetamine sulfate on time and brightness perception in human subjects. Psychopharmacologia (Berl.)3, 44–50 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kenna, J.C., Sedman, G. The subjective experience of time during lysergic acid diethylamide (LSD-25) intoxication. Psychopharmacologia 5, 280–288 (1964). https://doi.org/10.1007/BF02341260
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02341260