Abstract
A 77 year old woman was hospitalized one hour after the onset of right hemiplegia and aphasia. Magnetic resonance imaging (MRI) examination was negative and MRA indicated occlusion of the left middle cerebral artery. Treatment with streptokinase was instituted (a 60 minute intravenous infusion of 1.5 MU of streptokinase in 100 ml of saline solution). Two hours after infusion, the patient's motor function clearly improved. An MRA examination performed six hours later showed partial recanalization of the obstructed vessel.
Our report demonstrates the potential usefulness of MRA monitoring during thrombolytic therapy.
Sommario
Una donna di 77 anni fu ricoverata a distanza di un'ora dall'insorgenza di emiplegia destra con afasia. Una Risonanza Magnetica dell'encefalo risultò negativa, mentre una Angio-RM indicava l'occlusione dell'arteria cerebrale media di sinistra; fu quindi intrapresa la terapia con streptokinasi.
Dopo due ore dall'infusione, le capacità motorie della paziente migliorano sensibilmente. Una Angio-RM effettuata sei ore più tardi evidenziò la parziale ricanalizzazione del vaso occluso. Questo caso dimostra la potenziale utilità del monitoraggio con Angio-RM nel corso della terapia trombolitica.
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Federico, F., D'Aprile, P., Lamberti, P. et al. Magnetic resonance angiography monitoring of streptokinase in occlusion of the middle cerebral artery. Ital J Neuro Sci 14, 629–632 (1993). https://doi.org/10.1007/BF02339247
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DOI: https://doi.org/10.1007/BF02339247