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The Italian Journal of Neurological Sciences

, Volume 14, Issue 8, pp 629–632 | Cite as

Magnetic resonance angiography monitoring of streptokinase in occlusion of the middle cerebral artery

  • Federico F. 
  • D'Aprile P. 
  • Lamberti P. 
  • Abbinante A. 
  • Damiani M. 
  • Carella A. 
Case Reports

Abstract

A 77 year old woman was hospitalized one hour after the onset of right hemiplegia and aphasia. Magnetic resonance imaging (MRI) examination was negative and MRA indicated occlusion of the left middle cerebral artery. Treatment with streptokinase was instituted (a 60 minute intravenous infusion of 1.5 MU of streptokinase in 100 ml of saline solution). Two hours after infusion, the patient's motor function clearly improved. An MRA examination performed six hours later showed partial recanalization of the obstructed vessel.

Our report demonstrates the potential usefulness of MRA monitoring during thrombolytic therapy.

Key Words

Magnetic Resonance Imaging streptokinase occlusion 

Sommario

Una donna di 77 anni fu ricoverata a distanza di un'ora dall'insorgenza di emiplegia destra con afasia. Una Risonanza Magnetica dell'encefalo risultò negativa, mentre una Angio-RM indicava l'occlusione dell'arteria cerebrale media di sinistra; fu quindi intrapresa la terapia con streptokinasi.

Dopo due ore dall'infusione, le capacità motorie della paziente migliorano sensibilmente. Una Angio-RM effettuata sei ore più tardi evidenziò la parziale ricanalizzazione del vaso occluso. Questo caso dimostra la potenziale utilità del monitoraggio con Angio-RM nel corso della terapia trombolitica.

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Copyright information

© Masson Italia Periodici S.r.l. 1993

Authors and Affiliations

  • Federico F. 
    • 1
  • D'Aprile P. 
    • 2
  • Lamberti P. 
    • 1
  • Abbinante A. 
    • 1
  • Damiani M. 
    • 1
  • Carella A. 
    • 2
  1. 1.Clinica Neurologica IUniversità degli Studi di BariBariItalia
  2. 2.Cattedra di NeuroradiologiaUniversità degli Studi di BariBariItalia

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