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The Italian Journal of Neurological Sciences

, Volume 14, Issue 7, pp 579–580 | Cite as

Acute third cranial nerve ophthalmoplegia: Possible pathogenesis from alpha-II-interferon treatment

  • Pacifici L. 
  • Passarelli F. 
  • Papa G. 
  • Cannone L. 
  • Rossini P. M. 
Case Reports

Abstract

We report the case of a 67 year old man with acute ophthalmoplegia due to extensive damage to the fibers innervating the extrinsic muscles of the left third cranial nerve. The condition was secondary to protracted treatment with alpha-II-interferon for a HCV virus chronic active hepatopathy.

Key Words

Interferon neuropathy neurotoxicity adverse effects 

Sommario

Descriviamo il caso di un uomo di 67 anni che ha presentato acutamente una oftalmoplegia da danno alle fibre che innervano la muscolatura estrinseca del 3° nervo cranico di sinistra.

Questo quadro clinico appariva secondario a trattamento cronico con alfa-II-interferon, instaurato per una epatopatia cronica da HCV.

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Copyright information

© Masson Italia Periodici S.r.l. 1993

Authors and Affiliations

  • Pacifici L. 
    • 1
  • Passarelli F. 
    • 1
  • Papa G. 
    • 2
  • Cannone L. 
    • 3
  • Rossini P. M. 
    • 1
  1. 1.Divisione di NeurologiaOspedale “S. Giovanni Calibita” FatebenefratelliRomaItalia
  2. 2.Cattedra di EmatologiaII Università di RomaRomaItalia
  3. 3.NeurofisiopatologiaOspedale Civile di NettunoNettunoItalia

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