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The Italian Journal of Neurological Sciences

, Volume 11, Issue 5, pp 429–435 | Cite as

Usefulness and significance of the concept of leukoaraiosis in the study of dementia

  • Sanguineti I. 
  • Beghi E. 
  • Bogliun G. 
Article
  • 34 Downloads

Abstract

The term leukoaraiosis (LA), recently coined to designate the subcortical whitematter hypodensity most commonly seen on computerized tomography of the brain of demented and/or hypertensive subjects, is discussed with reference to the principal neurological disorders of the elderly. The contribution of published reports on LA are reviewed and some general comments are made in the light of the pathophysiology and classification of dementia.

Key-Words

Leukoaraiosis dementia cerebrovascular disease 

Sommario

Gli Autori prendono in considerazione l'utilità ed il significato del concetto di leucoaraiosi recentemente introdotto per definire descrittivamente l'ipodensità della sostanza bianca sottocorticale alla tomografia computerizzata, rilievo ormai sempre più frequente nelle affezioni del senium legate alla demenza e all'ipertensione arteriosa. A questo scopo ricordano le diverse forme morbose che più significativamente presentano questo rilievo, illustrano i contributi della letteratura e traggono alcune conclusioni in merito ai problemi dottrinali posti dalle demenze e a quelli legati alla loro classificazione.

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Copyright information

© Masson Italia Periodici 1990

Authors and Affiliations

  • Sanguineti I. 
    • 1
  • Beghi E. 
    • 1
    • 2
  • Bogliun G. 
    • 1
  1. 1.Dipartimento di NeurologiaOspedale S. GerardoMonza
  2. 2.Istituto di Ricerche Farmacologiche “Mario Negri”Milano

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