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Sympatho-renal interactions

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Abstract

The renal nerves appear to be involved in the control of cardiovascular homeostatis and volume balance both in physiological and in phatological conditions such as experimental hypertension. Anatomical and electophysiological evidence suggests that the kidney has a diffuse sensory innervation connected with areas in the brain and spinal cord that are known to regulate cardiovascular functions by both neural and humoral mechanisms. The demonstration of the existence of neural reno-renal reflexes controlling several renal functions indicates that a functional balance between the two kidneys exists and may play an important role in the moment-to-moment control of kydney functions.

Sommario

I nervi renali sembrano coinvolti nel controllo dell’omeastasi sia in condizioni fisiologiche che patologiche (come l’ipertensione sperimentale).

I dati anatomici ed elettrofisiologici dimostrano che il rene ha una diffusa innervazione nervosa sensoriale collegata con aree celebrali e spinali che sappiano essere in grado di regolare le funzioni cardiovascolari con meccanismi neurali ed umorali. La dimostrazione di riflessi neuronali reno-renali che controllano alcune funzioni renali indicano che esiste una bilancia funzionale tra i due reni ed essa può svolgere un importante ruolo nel controllo attimo per attimo delle funzioni renali.

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Authors and Affiliations

  1. Istituto di Clinica Medica Generale e Terapia Medica, Università di Milano, Via Sforza, 65-20122, Milano

    Zanchetti A.

  2. Centro di Fisiologia Clinica e Ipertensione, Ospedale Maggiore, Via Sforza, 65-20122, Milano

    Stella A.

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  1. Zanchetti A.
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Zanchetti, A., Stella, A. Sympatho-renal interactions. Ital J Neuro Sci 8, 477–485 (1987). https://doi.org/10.1007/BF02334604

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