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The Italian Journal of Neurological Sciences

, Volume 10, Issue 1, pp 69–72 | Cite as

Substance P-like immunoreactive nerve fibers of the human laryngeal mucosa—Preliminary report

  • Frigo B. 
  • Barbareschi M. 
  • Mariscotti C. 
  • Motta M. 
  • Felisati G. 
  • Pignataro L. 
  • Manghisi V. 
Original Articles

Abstract

Substance P (SP) is considered a primary sensory transmitter and is widely distributed within the autonomic nervous system.

This study is concerned with the distribution of SP-like immunoreactive nerve fibers in the human larynx. Individual SP-like immunoreactive nerve fibers were detected in the subepithelial connective tissue of the laryngeal mucosa, in the ventricular and subglottic glandular regions and in a few nervous ganglia in the deep connective tissue. No intraepithelial SP-like immunoreactive fibers were present in our material.

Key-Words

Substance P laringeal nerves human-immunocytochemistry 

Sommario

La sostanza P è considerata essere un importante neurotrasmettitore sensoriale, ampiamente distribuito all'interno del sistema nervoso autonomo.

Il presente studio è volto ad individuare la presenza di fibre nervose immunoreattive per la sostanza P, o per peptidi ad essa correlati, nel contesto della laringe umana. Si sono repertate singole fibre immunoreattive per la sostanza P a livello del connettivo subepiteliale della mucosa laringea, delle regioni ghiandolari ventricolare e sottoglottica e in alcuni rari gangli presenti nel tessuto connettivale profondo. Nel materiale in esame non si sono repertate fibre intraepiteliali.

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Copyright information

© Masson Italia Periodici 1989

Authors and Affiliations

  • Frigo B. 
    • 1
  • Barbareschi M. 
    • 1
  • Mariscotti C. 
    • 1
  • Motta M. 
    • 1
  • Felisati G. 
    • 2
  • Pignataro L. 
    • 2
  • Manghisi V. 
    • 3
  1. 1.III Cattedra di Anatomia ed Istologia PatologicaUniversità degli StudiMilano
  2. 2.II Cattedra di OtorinolaringologiaUniversità degli StudiMilano
  3. 3.Divisione di OtorinolaringologiaOspedale BassiniMilano

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