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Substance P-like immunoreactive nerve fibers of the human laryngeal mucosa—Preliminary report

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Abstract

Substance P (SP) is considered a primary sensory transmitter and is widely distributed within the autonomic nervous system.

This study is concerned with the distribution of SP-like immunoreactive nerve fibers in the human larynx. Individual SP-like immunoreactive nerve fibers were detected in the subepithelial connective tissue of the laryngeal mucosa, in the ventricular and subglottic glandular regions and in a few nervous ganglia in the deep connective tissue. No intraepithelial SP-like immunoreactive fibers were present in our material.

Sommario

La sostanza P è considerata essere un importante neurotrasmettitore sensoriale, ampiamente distribuito all'interno del sistema nervoso autonomo.

Il presente studio è volto ad individuare la presenza di fibre nervose immunoreattive per la sostanza P, o per peptidi ad essa correlati, nel contesto della laringe umana. Si sono repertate singole fibre immunoreattive per la sostanza P a livello del connettivo subepiteliale della mucosa laringea, delle regioni ghiandolari ventricolare e sottoglottica e in alcuni rari gangli presenti nel tessuto connettivale profondo. Nel materiale in esame non si sono repertate fibre intraepiteliali.

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Authors and Affiliations

  1. III Cattedra di Anatomia ed Istologia Patologica, Università degli Studi, Via Commenda, 19, 20122, Milano

    Frigo B., Barbareschi M., Mariscotti C. & Motta M.

  2. II Cattedra di Otorinolaringologia, Università degli Studi, Milano

    Felisati G. & Pignataro L.

  3. Divisione di Otorinolaringologia, Ospedale Bassini, Milano

    Manghisi V.

Authors
  1. Frigo B.
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  2. Barbareschi M.
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  3. Mariscotti C.
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  4. Motta M.
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  5. Felisati G.
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  6. Pignataro L.
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  7. Manghisi V.
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Frigo, B., Barbareschi, M., Mariscotti, C. et al. Substance P-like immunoreactive nerve fibers of the human laryngeal mucosa—Preliminary report. Ital J Neuro Sci 10, 69–72 (1989). https://doi.org/10.1007/BF02333874

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  • DOI: https://doi.org/10.1007/BF02333874

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