Skip to main content
Log in

Polymorphism of the third component (C3) of complement and of transferrin (Tf) in Belgium

  • Originalarbeiten / Original Papers
  • Published:
Zeitschrift für Rechtsmedizin Aims and scope Submit manuscript

Summary

The phenotypes of C3 and of Tf were determined in 818 and 576, respectively, unrelated individuals living in Liege. The gene frequencies observed are:

C3S:

0.811

C3F:

0.186

C3Var:

0.003

TfC:

0.990

TfB:

0.007

TfD:

0.003

The application to disputed paternity cases and to the study of twins is discussed.

Zusammenfassung

Die Bestimmung der C3 — und Tf — Phänotypen bei 818, beziehungsweise 576, Einwohnern von Liege (Belgien) ergab folgende Genfrequenzen:

C3S:

0.811

C3F:

0.186

C3Var:

0.003

TfC:

0.990

TfB:

0.007

TfD:

0.003

Die Verwendung dieser Gruppen in der Vaterschaftsbegutachtung und bei Zwillingenuntersuchungen wird diskutiert.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Alper, C. A., Propp, R. P.: Genetic Polymorphism of the Third Component of Human Complement (C′3). J. Clin. Invest.47, 2181–2191 (1968)

    CAS  PubMed  Google Scholar 

  2. Arvilommi, H.: Genetic Polymorphism of Serum C3 in Finns. Vox Sang.25, 9–27 (1973)

    Google Scholar 

  3. Azen, E. A., Smithies, O.: Genetic Polymorphism of C′3 (B1 C-globulin) in human serum. Science162, 905–907 (1968)

    CAS  PubMed  Google Scholar 

  4. Bronnestam, R., Beckman, L., Cedergren, B.: Genetic Polymorphism of the Complement Component C3 in Swedish Lapps. Human Hered.21, 267–271 (1971)

    CAS  Google Scholar 

  5. Dissing, J., Sorensen, H.: Studies on C′3 Polymorphism in Denmark. Human Hered.21 272–277 (1971)

    CAS  Google Scholar 

  6. Goedde, H. W., Benkmann, H. G., Agarwal, D. P., Hirth, L.: Further Investigation on the Inherited Polymorphism of the Third Component of Complement (B1 C/B1 A-globulin). Human Hered.22, 488–495 (1972)

    CAS  Google Scholar 

  7. Kuhnl, P., Spielmann, W.: Untersuchungen zum C3-Polymorphismus (B1 C-globulin) Genfrequenzen und Familienuntersuchungen an hessischen Blutspendern und Bantupopulation Heumangenetik15, 7–13 (1972)

    CAS  Google Scholar 

  8. Mauff, G., Potrafki, B. G., Freis, H., Pulverer, G.: Vergleichende Untersuchungen zum Polymorphismus des Posttransferrins (Pt) und der dritten Komponente des Humankomplements (C3). Humangenetik21, 75–80 (1974)

    CAS  PubMed  Google Scholar 

  9. Pflugshaupt, R., Scherz, R., Steinegger, L., Butler, R.: The Frenquency of the Polymorphisms of C3 in the Swiss Population and some remarks on the identification of rare phenotypes. Protides of the Biological Fluids. 22nd Colloq. 1975

  10. Rittner, C., Rittner, B.: Report 1973/1974 of the Reference Laboratory for the Polymorphism of the Third Component (C3) Vox Sang.27, 464–472 (1974)

    CAS  PubMed  Google Scholar 

  11. Smithies, O.: Variations in human serum B-globulins. Nature (Lond.)180, 1482 (1957)

    CAS  Google Scholar 

  12. Teisberg: High Voltage Agarose Gel Electrophoresis in the Study of C3 Polymorphism. Vox. Sang.19, 47–56 (1970)

  13. Teisberg, P.: The Distribution of C3 Types in Norway. Human Hered.21, 154–161 (1971)

    CAS  Google Scholar 

  14. Teisberg, P.: C3 Types of Norvegian Lapps. Human Hered.21, 162–167 (1971)

    CAS  Google Scholar 

  15. Wieme, R. J., Demeulenaere, L.: Genetically determined electrophoretic variant of the human complement component C′3. Nature (Lond.)214, 142 (1967)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hoste, B., Brocteur, J., Suys, J. et al. Polymorphism of the third component (C3) of complement and of transferrin (Tf) in Belgium. Z Rechtsmed 80, 55–59 (1977). https://doi.org/10.1007/BF02332348

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02332348

Key words

Navigation