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Germacranolide fromTanacetopsis mucronata

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Abstract

A sesquiterpene lactone of the germacrane series, mucrochin, has been isolated from the epigeal part ofTanacetopsis mucronata, and its structure has been studied by IR and mass spectral methods and PMR spectroscopy. It structure has been determined unambiguously by x-ray structural analysis as 5,6-dihydroxy-5α,6β,7α,8β(H)-germacra-1(10),4(15) 1(13)-trien-8,12-olide. A boat-chair conformation with a configuration of the1D14 15D5 type has been established.

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Authors and Affiliations

  1. Pharmaceutical Institute, pr. Aibeka 45, 15, Tashkent

    M. B. Izbosarov & B. Kh. Abduazimov

  2. Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent

    I. M. Yusupova, B. Tashkhodzhaev, A. D. Vdovin & N. D. Abdullaev

Authors
  1. M. B. Izbosarov
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  2. B. Kh. Abduazimov
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  3. I. M. Yusupova
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  4. B. Tashkhodzhaev
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  5. A. D. Vdovin
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  6. N. D. Abdullaev
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Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 492–498, July–August, 1998.

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Izbosarov, M.B., Abduazimov, B.K., Yusupova, I.M. et al. Germacranolide fromTanacetopsis mucronata . Chem Nat Compd 34, 456–461 (1998). https://doi.org/10.1007/BF02329594

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  • DOI: https://doi.org/10.1007/BF02329594

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