Pediatric Cardiology

, Volume 10, Issue 1, pp 53–55 | Cite as

Aortic root dilatation associated with partial trisomy 7(q31.2→qter)

  • K. B. Roche
  • John W. Moore
  • Rawatal B. Surana
  • Bruce E. Wilson
Article

Summary

Aortic root dilatation and mitral valve prolapse are cardiac findings sometimes seen in disorders of connective tissue, most often in the Marfan syndrome. This report describes an infant with these cardiac anomalies and a specific chromosomal abnormality, partial trisomy of chromosome 7 associated with partial monosomy of chromosome 22. This association may have significance with respect to the etiology of cardiac disease in connective tissue disorders such as Marfan syndrome.

Key words

Marfan syndrome Aortic root dilatation Trisomy 7 

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Copyright information

© Springer-Verlag New York Inc 1989

Authors and Affiliations

  • K. B. Roche
    • 1
  • John W. Moore
    • 1
  • Rawatal B. Surana
    • 2
  • Bruce E. Wilson
    • 1
  1. 1.Department of Pediatrics and the Section of Pediatric CardiologyWalter Reed Army Medical CenterWashington, DC
  2. 2.Department of Pediatric PathologyArmed Forces Institute of PathologyWashington, DCUSA

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