Summary
The analytical roles of chromatographic variables (column length, etc.) can be soundly comprehended and compared in terms of the precision (Φ) of measurements and efficiency (ϑ) of analysis which are described as Shannon information and information flow, respectively. The φϑ plots of the optimization process and the information Φ transmitted by a single peak are useful to understand the analytical structure of optimization. Variables treated here are mobile phase composition (X), column length (L), mobile phase velocity rate (u), detection wavelength (λ) and plate number (N).
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Y. Hayashi, R. Matsuda, Chromatographia30, 367 (1990).
Y. Hayashi, R. Matsuda, Fresenius J. Anal. Chem., submitted for publication.
Y. Hayashi, R. Matsuda, A. Nakamura, Chromatographia30, 85 (1990).
Y. Hayashi, Anal. Sci.,6, 257 (1990).
S. N. Deming, J. M. Palasota, J. Lee, L. Sun, J. Chromatogr.485, 15 (1989).
D. L. Massart, B. G. M. Vandeginste, S. N. Deming, Y. Michotte, L. Kaufman, Chemometrics: a textbook, Elsevier, Amsterdam, 1988, Chapter 2.
J. C. Berridge, J. Chromatogr.485, 3 (1989).
H. J. G. Debets, B. L. Bajema, D. A. Doornbos, Anal. Chim. Acta,151, 131 (1983).
H. A. H. Billiet, L. de Galan, J. Chromatogr.485, 27 (1989).
K. Jinno, K. Kawasaki, J. Chromatogr.,298, 326 (1984).
C. E. Goewie, J. Liquid Chromatogr.,9, 1431 (1985).
P. J. Schoenmakers, J. Liquid Chromatogr.,10, 1865 (1987).
J. L. Glajch, J. J. Kirkland, J. M. Minor, J. Liquid Chromatogr.,10, 1727 (1987).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Matsuda, R., Hayashi, Y. Information theory of optimization in chromatography: Analytical structure of optimization. Chromatographia 30, 371–376 (1990). https://doi.org/10.1007/BF02328500
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02328500