, Volume 25, Issue 4, pp 402–428 | Cite as

Structure of chromosomes

I. Morphological studies of the spiral structure of human somatic chromosomes
  • Yasushi Ohnuki


The number of gyres, mode, and direction of coils, centromere, secondary constriction, and telomere were studied in the human somatic chromosomes in terms of spiral structure, employing the newly developed technique involving a hypotonic treatment. Results obtained are: 1. the number of gyres is most probably constant in analogous chromosome from different cells; 2. the direction of coils is random; 3. each ehromatid is accepted as a unit of chromonema coiling; 4. the centromere seems to be a regionally elongated portion of the chromonema, without showing any differentiated structure; 5. chromonemata at secondary constrictions usually appear as uncoiled or less tightly coiled entities, and 6. two different types of the telomere structure were observed, one being a pointed-end type, while the other is a rounded-end type (Summary see p. 424).


Developmental Biology Somatic Chromosome Spiral Structure Secondary Constriction Hypotonic Treatment 
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Copyright information

© Springer-Verlag 1968

Authors and Affiliations

  • Yasushi Ohnuki
    • 1
  1. 1.Pasadena Foundation for Medical ResearchPasadena

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