Summary
Isolated rat liver nuclei have been analyzed for the intranuclear concentration of 8 glycolytic metabolites, and in addition for the 3 adenine nucleotides, and for malate. All these substrates are to be found in nuclei in a range of concentration comparable to that in the whole tissue. The consequences of these findings with respect to the definite establishment of glycolysis in isolated nuclei, as well as for the intranuclear formation of energy-rich phosphate bonds, are discussed.
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References
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Meinem Lehrer, Prof. Dr. Dr.K. Lang, in aller Verehrung und Dankbarkeit zum 60. Geburtstag gewidmet.
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Siebert, G. Bestimmung von Glykolyse-Metaboliten in isolierten Zellkernen. Experientia 14, 449 (1958). https://doi.org/10.1007/BF02327367
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DOI: https://doi.org/10.1007/BF02327367