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Chemical excitability of axons: Excitatory and inhibitory effects of putative neurotransmitters and modulators on frog sciatic nerves

  • Physiologica
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Summary

The microiontophoretic administration of putative neuromodulators (acetylcholine, norepinephrine, dopamine, 2-phenylethylamine, tryptamine, histamine) triggered firing or inhibited on-going activity in isolated frog sciatic nerves.

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Authors and Affiliations

  1. Department of Pharmacology, University of Health Sciences, The Chicago Medical School and Department of Anesthesiology Mount Sinai Hospital, 2020 West Ogden Avenue, 60612, Chicago, (Illinois), (USA)

    H. C. Sabelli & Joan May

Authors
  1. H. C. Sabelli
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  2. Joan May
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Additional information

This research was supported by the National Institute of Mental Health (grant No. MH-14110) and by the Anesthesiology Research Fund. The authors wish to thank Dr.H. H. Havdala for his encouragement and collaboration, and Ms.Anna Maslanka and Ms.Linda Wilson for excellent technical assistance.

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Sabelli, H.C., May, J. Chemical excitability of axons: Excitatory and inhibitory effects of putative neurotransmitters and modulators on frog sciatic nerves. Experientia 31, 1049–1051 (1975). https://doi.org/10.1007/BF02326953

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  • DOI: https://doi.org/10.1007/BF02326953

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