, Volume 31, Issue 10, pp 1233–1234 | Cite as

Production of antibodies to amanitins as the basis for their radioimmunoassay

  • L. Fiume
  • C. Busi
  • G. Campadelli-Fiume
  • C. Franceschi
Haematologica, Immunologica


The production of antibodies against amanitins is described. By means of these antibodies, a radioimmunoassay was developed which allows detection of as little as 0.5 ng of amanitins in 1 ml of serum. By this method, the clearance of α-amanitin from the blood of poisoned mice was measured.


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Copyright information

© Birkhäuser Verlag 1975

Authors and Affiliations

  • L. Fiume
    • 1
  • C. Busi
    • 1
  • G. Campadelli-Fiume
    • 1
  • C. Franceschi
    • 1
  1. 1.Istituto di Patologia generale and Istituto di Microbiologia e VirologiaUniversity of BolognaBologna(Italy)

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