, Volume 31, Issue 10, pp 1212–1213 | Cite as

Pentobarbital sodium and chromosome abnormalities in rabbit blastocysts

  • Evelyn L. Shaver
Anatomica, Histologica, Embryologica, Carcinologica


Female rabbits were injected with pentobarbital sodium at 1/4 h or 6 h post coitum. A slight delay in oocyte maturation was evident in animals killed at 17 h pc, however, zygote development appeared normal by 24 h pc. At 6 days pc, a greater frequency of chromosomally abnormal blastocysts was found in animals injected with pentobarbital than in control rabbits.


Sodium Pentobarbital Chromosome Abnormality Pentobarbital Sodium Great Frequency 


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Copyright information

© Birkhäuser Verlag 1975

Authors and Affiliations

  • Evelyn L. Shaver
    • 1
  1. 1.Department of Anatomy, Health Sciences CentreUniversity of Western OntarioLondonCanada)

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