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Pentobarbital sodium and chromosome abnormalities in rabbit blastocysts

  • Anatomica, Histologica, Embryologica, Carcinologica
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Summary

Female rabbits were injected with pentobarbital sodium at 1/4 h or 6 h post coitum. A slight delay in oocyte maturation was evident in animals killed at 17 h pc, however, zygote development appeared normal by 24 h pc. At 6 days pc, a greater frequency of chromosomally abnormal blastocysts was found in animals injected with pentobarbital than in control rabbits.

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Authors and Affiliations

  1. Department of Anatomy, Health Sciences Centre, University of Western Ontario, London, Ontario, Canada

    Evelyn L. Shaver

Authors
  1. Evelyn L. Shaver
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Additional information

This work was supported by a grant from the Medical Research Council of Canada.

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Shaver, E.L. Pentobarbital sodium and chromosome abnormalities in rabbit blastocysts. Experientia 31, 1212–1213 (1975). https://doi.org/10.1007/BF02326800

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  • DOI: https://doi.org/10.1007/BF02326800

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