, Volume 31, Issue 10, pp 1130–1132 | Cite as

Renal glucose utilization in genetically diabetic microangiopathy

  • M. Chen
  • C. Velasco
  • R. A. Camerini-Davalos
Specialia Chimica, Biochimica


Glucose uptake into kidney tissue is not influenced by the development of glomerulosclerosis in KK mice. Glucosyltransferase activity remains at a normal level even at an age having a highest incidence of serious development of glomerulosclerosis. The observation suggests that biosynthesis of basement membrane reflected by its glucosyltransferase activity does not accelerate in genetically transmitted microangiopathy.


Glucose Normal Level Basement Membrane Glucose Uptake Glucose Utilization 
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Copyright information

© Birkhäuser Verlag 1975

Authors and Affiliations

  • M. Chen
    • 1
    • 2
  • C. Velasco
    • 1
  • R. A. Camerini-Davalos
    • 1
  1. 1.Department of BiochemistryPurdue UniversityWest LafayetteUSA
  2. 2.Diabetes Center, Department of MedicineNew York Medical CollegeNew YorkUSA

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