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Stimulation of trophoblastic giant cell differentiation in the homozygousYellow mouse embryo

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Abstract

Escape from pre-implantation lethality by homozygousyellow embryos depends on differentiation of trophoblastic cells. The evidence presented herein suggests that progesterone stimulated differentiation of trophoblastic giant cells in some homozygousyellow blastocysts and thereby increased the percentage ofA y/Ay “escaper” embryos.

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References

  • Dickson, A. D. (1967). Induction of the trophoblast giant-cell transformation after ovariectomy in the mouse.J. Embryol. Exp. Morph. 17: 189–193.

    CAS  PubMed  Google Scholar 

  • Eaton, G. J. & M. M. Green (1962). Implantation and lethality of theyellow mouse.Genetica 33: 106–113.

    Google Scholar 

  • Eaton, G. J. & M. M. Green (1963). Giant cell differentiation and lethality of homozygousyellow mouse embryos.Genetica 34: 155–161.

    Google Scholar 

  • Potts, D. M. & I. R. Wilson (1967). The preimplantation conceptus of the mouse at 90 hourspost coitum.J. Anat. 102: 1–11.

    Google Scholar 

  • Robertson, G. G. (1942). An analysis of the development of homozygousyellow mouse embryos.J. Exp. Zool. 89: 197–231.

    Article  Google Scholar 

  • Wolff, G. L. & A. Bartke (1966). Decreased survival of embryos inyellow (Ay/a) female mice.J. Hered. 57: 14–17.

    CAS  PubMed  Google Scholar 

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This work was supported in part by funds from research grant HDOOO36, National Institute of Child Health and Development, National Institutes of Health, U.S.A.

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Eaton, G.J. Stimulation of trophoblastic giant cell differentiation in the homozygousYellow mouse embryo. Genetica 39, 371–378 (1968). https://doi.org/10.1007/BF02324477

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  • DOI: https://doi.org/10.1007/BF02324477

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