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Chromatographia

, Volume 28, Issue 3–4, pp 212–216 | Cite as

Chiral bonded packings for liquid chromatography: Preparation and evaluation of N-acylated aminoacid packings based on aminopropylated silica gel

  • J. N. Akanya
  • D. R. Taylor
Originals

Summary

N-Protected single amino acid residues have been chemically bound to aminopropylated silica gel to give chiral HPLC column packings. Surface coverages have been determined by both elemental and aminoacid analyses. In addition, the nature of the surface-bound groups has been studied by reflectance fourier transform infrared (FTIR) spectroscopy. The resolution of a range of racemic mixtures has been achieved using the column packings.

Key Words

Column liquid chromatography Chiral bonded phases Enantiomer separations Amino acid esters 

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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1979

Authors and Affiliations

  • J. N. Akanya
    • 1
  • D. R. Taylor
    • 2
  1. 1.Chemistry DepartmentFederal University of TechnologyMinnaNigeria
  2. 2.Chemistry DepartmentUniversity of Manchester, Institute of Science and TechnologyManchesterUK

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