Chromatographia

, Volume 27, Issue 9–10, pp 469–471 | Cite as

Headspace gas chromatographic analysis for the determination of traces of ethylene oxide in sterilized materials

  • M. V. Russo
Short Communications

Summary

A headspace gas chromatographic method for determination of traces of ethylene oxide (EO) in sterilized materials has been developed. The method allows the determination of the amount of EO by putting the samples directly into acetonitrile and analysing by means of headspace GC.

The procedure described is simple, sensitive, reproducible and linear. The lower limit of detection is 0.015 μg/g of sterilized material.

Key Words

Gas chromatography Headspace analysis Ethylene oxide Capillary column 

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References

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    Z. Glaser, in “Toxicological and Carcinogenic Health Hazards in the Workplace, First Annual NIOSH Scientific Symposium” (K. Bridbord andJ. French, eds.) Sponsored by NIOSH, Center of Diseases Control, Rockville, Md., 1978.Google Scholar
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    NIOSH “Registry of Toxic Effects of Chemical Substances (RTECS)”, File on-line, National Library of Medicine of Bethesda.Google Scholar
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    M. V. Russo, G. Goretti, A. Liberti, J. HRC & CC,8, 535 (1985).Google Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1989

Authors and Affiliations

  • M. V. Russo
    • 1
  1. 1.Dipartimento di ChimicaUniversità “La Sapienza” RomaRomaItaly

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