Advertisement

Chemistry of Heterocyclic Compounds

, Volume 34, Issue 2, pp 171–173 | Cite as

Alkylation of 1-methyl-2-benzimidazolylacetonitrile

  • Yu. M. Volovenko
Article

Abstract

Alkylation of 1-methyl-2-benzimidazolylacetonitrile by esters of α-halogenocarboxylic acids and chloromethylarenes in dimethylformamide in the presence of potassium carbonate proceeds at the carbon atom of the methylene group.

Keywords

Methylene Ester Potassium Organic Chemistry Carbon Atom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    P. M. Kochergin, A. A. Druzhinina, and R. M. Palei, Khim. Geterotsikl. Soedin., No. 11, 1549 (1976).Google Scholar
  2. 2.
    É. R. Zakhs, M. A. Subbotina, and A. V. El'tsov, Zh. Org. Khim.,15, 200 (1979).Google Scholar
  3. 3.
    V. A. Anisimova, O. I. Askalepova, K. N. Bagdasarov, and M. S. Chernov'yants, Khim. Geterotsikl. Soedin., No. 3, 345 (1988).Google Scholar
  4. 4.
    T. P. Burhholder, E. M. Kudlacz, M. E. Lester, and S. W. Horgan, Bioorg. Med. Chem. Lett.,6, No. 8, 951 (1996).Google Scholar

Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • Yu. M. Volovenko

There are no affiliations available

Personalised recommendations